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Clinical Trials/CTRI/2025/08/093451
CTRI/2025/08/093451
Not yet recruiting
Phase 2

An Open Label Comparative Randomized Clinical Trial to Evaluate the efficacy of Bruhatyadi Yapana Basti and Patoladi Niruha Basti In the Management of Asthimajjagata Vata W.S.R Avascular Necrosis (AVN) of the Femoral Head

Institute For Ayurved Studies And Research1 site in 1 country40 target enrollmentStarted: November 15, 2025Last updated:

Overview

Phase
Phase 2
Status
Not yet recruiting
Sponsor
Institute For Ayurved Studies And Research
Enrollment
40
Locations
1
Primary Endpoint
Reduction in AsthiShoola Pain in Bones As Per Ayurvedic Criteria

Overview

Brief Summary

This study is a Randomized Open Label Clinical trial to evaluate the efficacy of Bruhatyadi Yapana Basti and Patoladi Niruha Basti in managing Asthimajjagata Vata with special reference to Avascular Necrosis of the Femoral head  AVN is a progressive degenerative disorder caused by impaired blood supply parallel symptoms  of Asthimajjagata Vata described in Ayurveda contemporary treatments like surgery have limitations whereas basti therapy offers a safe cost effective alternative Forty Patient will be randomly allocated into two groups receiving 16 days of Kala basti regimen The trial aims to compare symptomatic relief functional improvement and potential disease modifying outcomes

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
None

Eligibility Criteria

Ages
25.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patient Having Classical Signs And Symptoms Of Asthimajjagata Vata Patient Having Sign And Symptoms Of Avascular Necrosis Of Femoral Head Either Unilateral Or Bilateral Of Any Stages Patients Yogya For Basti Karma.

Exclusion Criteria

  • Patient Who Is Contraindicated For Basti Patient With Chronic Systemic Illness Cardiac Disease Cirrhosis Of Liver Diabetes Hypertension Chronic Renal Disease Carcinoma Pregnant And Lactating Women Patient With Ano Rectal Disease Patient Of AVN With Fractured Dislocation Severly Deformed Hip Joint Patient Unwilling To Participate In The Trial Patient Aged Below 25 Years And Above 60 Years.

Outcomes

Primary Outcomes

Reduction in AsthiShoola Pain in Bones As Per Ayurvedic Criteria

Time Frame: 1st- 0 day | 2nd- 16th day | 3rd- 32nd day | 4th- 48th day

Secondary Outcomes

  • Improvement In Mamsakshaya Muscles Hypotonia Aswapan Santat Ruka Sleeplessness Due To Continuous Pain Balakshaya Muscle Power Grading As Per Ayurvedic Criteria(Follow Up on 16th 32nd 48th Day)

Investigators

Sponsor
Institute For Ayurved Studies And Research
Sponsor Class
Research institution and hospital
Responsible Party
Principal Investigator
Principal Investigator

Dr Sunita

Institute For Ayurved Studies And Research

Study Sites (1)

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