Association of Cardiovascular Health During Pregnancy With Perinatal Outcomes---a Birth Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pregnant Women
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
- Enrollment
- 5000
- Locations
- 3
- Primary Endpoint
- Neonatal outcomes
- Status
- Recruiting
- Last Updated
- 4 months ago
Overview
Brief Summary
Pregnancy is a critical period for cardiovascular health risk assessment and interventions to reduce the incidence of cardiovascular disease in both mother and child generations. Recently, the American Heart Association proposed the latest cardiovascular health assessment indicator "Life's Essential 8". However, there is still a lack of application data for pregnant women. This project intends to explore the application potential of Life's Essential 8 in cardiovascular health assessment of pregnant women and establish appropriate gestaional cardiovascular health standards.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Maternal age: 20-49 years;
- •Natural conception;
- •Single pregnancy;
- •Plan to have routine prenatal examinations and give birth in the research center;
Exclusion Criteria
- •Have diseases that affect metabolic function or even threaten the life of the mother and fetus before pregnancy;
- •Assisted reproduction;
- •Multiple pregnancy;
- •Fetus has a known deformity or genetic defects;
- •Incomplete clinical data.
Outcomes
Primary Outcomes
Neonatal outcomes
Time Frame: Through delivery completion, up to 42 weeks
Birth weight（in gram), birth height (in centimetre), gestational week (in week) and other neonatal diseases. They are diagnosed by clinicians and the data is gathered from medical records.
Maternal outcomes
Time Frame: Through delivery completion, up to 42 weeks
Including pregnancy-induced hypertension, preterm delivery, abortion, delivery way and so on. They are diagnosed by clinicians and the data is gathered from medical records.