NCT01838993Unknown不适用
The Effect of Ultrasonic Nebulizer Delivered Lidocaine on Circulatory Responses During Tracheal Intubation and Postoperative Sore Throat
New Taipei City Hospital1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2013年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Blood pressure
研究概览
简要总结
We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.
详细描述
Sudden increases in blood pressure and heart rate after tracheal intubation and post-operative sore throat are two common undesirable side effects of general anesthesia and might lead to patients' morbidity or dissatisfaction. We investigated the possibility to attenuate both side effects with one single method, i.e. ultrasound-driven lidocaine inhalation immediately before induction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists (ASA) physical status I or II. Patients scheduled for elective surgery under general anesthesia with orotracheal intubation
排除标准
- •patient's refusal to join, major surgery or expected operation duration longer than 3 hours, patients with a anticipated difficult airway, requiring a nasogastric tube in peri-operative stage, having recent upper respiratory tract infection (within 1 week) or pre-existing sore throat.
研究组 & 干预措施
Lidocaine
Active Comparator
Inhalation of lidocaine before intubation
干预措施: Lidocaine inhalation (Drug)
Control
Placebo Comparator
Normal saline inhalation before intubation
干预措施: Placebo (Drug)
结局指标
主要结局
Blood pressure
时间窗: 3 min
Non invasive blood pressure every min for 3 min
次要结局
- Post operative sore throat(3 days)
研究者
Chen Yen-Po
Physician
New Taipei City Hospital
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Effect of Nebulized Lidocaine on the Quality of Laryngeal Mask Airway InsertionAirway Complication of AnesthesiaNCT03361397Assiut University80
尚未招募
1 期
The interest of preoperative lidocaine 2% nebulization among children with a cold undergoing ambulatory surgery : a randomized controlled trialRespiratoryPaediatricsPACTR202402589581256Hedi Chaker university hospital100
已完成
4 期
Aerosolized Endotracheal Lidocaine to Avoid Intracranial Pressure Spikes in Patients With Severe Traumatic Brain InjuryTraumatic Brain InjuryNCT05058677The University of Texas Health Science Center, Houston10
已完成
1 期
Effect of Lidocaine Phonophoresis Versus Pulsed Ultrasound on Myofascial Pain Syndrome in Athletic ChildrenTreatment Side EffectsNCT04185194Cairo University50
已完成
不适用
Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated InfantsPulmonary AtelectasisNCT02584023Seoul National University Hospital40