Plasma Von Willebrand factor (vWF) assay compared to Prothrombin time (PT/INR), aPTT and Platelets as predictor of outcome in Alcoholic-Acute-on-chronic-liver failure (A-ACLF)
Not Applicable
- Conditions
- Acute on Chronic Liver failure
- Registration Number
- JPRN-UMIN000036660
- Lead Sponsor
- Christian Medical College Hepatology Department Vellore, Tamilnadu, India Zip: 632004 liverresearch@cmcvellore.ac.in
- Brief Summary
vWF levels are markedly elevated, correlate with organ failure, and predict in-hospital survival in Alcoholic-ACLF patients. vWF assays (vWF-Ag & vWF-CBA) as predictor of composite poor outcome was comparable to other severity score like MELD and was superior to PT/INR, aPTT and Platelets.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with hepatocellular carcinoma or portal vein thrombosis and those unwilling to participate were excluded from this study. Pregnant women and children were also excluded.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method