Which maintenance intravenous fluid therapy is best in children?
Not Applicable
Completed
- Conditions
- Health Condition 1: Z750- Medical services not available inhome
- Registration Number
- CTRI/2021/08/035924
- Lead Sponsor
- AIIMS Bhubaneswar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 142
Inclusion Criteria
Children who are planned to receive more than 50% of total calculated maintenance intravenous fluids.
Exclusion Criteria
Any condition which requires change of maintenance fluids
Known case of CKD/ congenital or acquired severe liver disease/ Diabetes insipidus and Diabetes mellitus.
Conditions / Procedural fluid therapy in which intravenous fluids were expected to be given for shorter duration than 6 h example any planned procedure like C.T/MRI Scans
Conditions causing changes in chloride levels example: Barter syndrome, Congenital Adrenal Hyperplasia etc
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To calculate the mean difference of hyperchloremia in children receiving 5% Dextrose in Ringerâ??s Lactate versus 5% Dextrose Normal Saline at 24 and 48hrs after start of fluids.Timepoint: To calculate the mean difference of hyperchloremia in children receiving 5% Dextrose in Ringerâ??s Lactate versus 5% Dextrose Normal Saline at 24 and 48hrs after start of fluids.
- Secondary Outcome Measures
Name Time Method Proportion of children developing Acute Kidney Injury as defined below in both groupsTimepoint: 24 and 48 hours;Proportion of children developing dyselectrolytemia (hyperchloremia, hypochloremia, <br/ ><br> hypernatremia, hyponatremia, hyperkalemia and hypokalemia) as defined below in both groupsTimepoint: 24 and 48 hours;Proportion of children developing hyperchloremic metabolic acidosis as defined below in both groupsTimepoint: 24 and 48 hours;To estimate all-cause mortality in both groups.Timepoint: Any time in hospital