Renal impairment in decompensated heart failure.

Not Applicable

• Conditions: Decompensated heart failure; Acute renal failure; Renal and Urogenital - Other renal and urogenital disorders; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12606000137594
• Lead Sponsor: Professor Mark Richards, Professor in Medicine, Christchurch School of Medicine and Health Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-04-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1) All individuals hospitalised at a tertiary-level hospital with the primary diagnosis of decompensated heart failure.

Exclusion Criteria

1) Severe stenotic valvular disease2) Women of childbearing age3) Exposure to iodinated contrast during the hospital admission4) Contraindication to magnetic resonance imaging.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prospective systematic documentation of the prevalence of renal dysfunction in an unselected population hospitalised with decompensated heart failure[Measured during index hospitalisation and at 6 and 12 months follow up.];Prospective systematic documentation of the incidence of renal dysfunction in an unselected population hospitalised with decompensated heart failure[Measured during index hospitalisation and at 6 and 12 months follow up.];Prospective systematic documentation of the severity of renal dysfunction in an unselected population hospitalised with decompensated heart failure[Measured during index hospitalisation and at 6 and 12 months follow up.];Prospective systematic documentation of the evolution of renal dysfunction in an unselected population hospitalised with decompensated heart failure[Measured during index hospitalisation and at 6 and 12 months follow up.]

Secondary Outcome Measures

Name	Time	Method
1) To examine the diagnostic and prognostic utility of plasma and urine biomarkers of acute kidney injury in decompensated heart failure.[During admission and at 6 months follow up.];2) To describe the changes in renal blood flow in human decompensated heart failure.[At admission and at 6 months follow up.];3) To examine the 6- and 12-month renal outcomes after hospitalisation with heart failure and their relationship to cardiac function.[]