Comparison of video laryngoscope with direct laryngoscope for the effect of laryngoscopy and intubation on optic nerve sheath diameter in adult patients undergoing laparoscopic cholecystectomy
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- 1. Optic nerve sheath diameter
研究概览
简要总结
To compare video laryngoscope with direct laryngoscope for the effect of laryngoscopy and intubation on optic nerve sheath diameter in adult patients undergoing laparoscopic cholecystectomy.
Primary objective: To compare C-MAC video laryngoscope with direct laryngoscope for the effect on Optic Nerve Sheath Diameter (ONSD) measured by trans ocular ultrasound at 1,3 and 5 minutes after laryngoscopy and intubation in adult patients undergoing laparoscopic cholecystectomy
Secondary objectives:
A. To compare C-MAC video laryngoscope with direct laryngoscope for the effect on Heart Rate (HR), Systolic blood pressure (SBP), Diastolic blood pressure (DBP) & Mean arterial pressure (MAP) at 1,3 &5 minutes post laryngoscopy and intubation.
B. To measure optic nerve sheath diameter (ONSD) by trans ocular ultrasound, Heart Rate (HR), Systolic blood pressure (SBP), Diastolic blood pressure (DBP) & Mean arterial pressure (MAP) at 1. 10 & 60 minutes after insufflation of pneumoperitoneum 2. 10 minutes after desufflation of pneumoperitoneum in supine position.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 and ASA 2 patients undergoing laparoscopic cholecystectomy.
排除标准
- •Patients with anticipated difficult airway, neurological conditions, patients with history of eye infections and diabetic retinopathy, history of intracranial or intraocular surgery.
结局指标
主要结局
1. Optic nerve sheath diameter
时间窗: 1. At baseline | 2. 1,3 & 5 minutes after intubation | 3. 10 and 60 minutes after insufflation of pneumoperitoneum | 4.10 minutes after desufflation of pneumoperitoneum
次要结局
- 1. Systolic Blood Pressure(2. Diastolic Blood Pressure)
研究者
Santhosh Kumar A
Vardhman Mahavir Medical College and Safdarjung Hospital