SMAS: a Prospective Study in a Single Institution

Not Applicable

Completed

• Conditions: Superior Mesenteric Artery Syndrome
• Interventions: Procedure: Duodenojejunostomy

• Registration Number: NCT03416647
• Lead Sponsor: Azienda Ospedaliera di Padova

Brief Summary

Superior Mesenteric Artery Syndrome (SMAS) is a rare cause of duodenal obstruction, that should be suspected in cases of chronic, refractory upper digestive symptoms. Between 2008 and 2016, 39 consecutive patients with chronic gastrointestinal symptoms and a diagnosis of SMAS were prospectively included in the study, in order to describe their demographic, clinical and outcome features. All patients underwent duodenojejunostomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-10
• Primary Completion: 2016-05
• Study Completion: 2017-02
• Study First Submitted: 2017-12-18
• Status Verified: 2018-01
• Study First Submitted QC: 2018-01-24
• Last Update Submitted: 2018-01-24
• Study First Posted: 2018-01-31
• Last Update Posted: 2018-01-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

Not provided

Exclusion Criteria

• inability to provide the informed consent;
• malignancies;
• bowel motility disorders;
• severe psychiatric illness;
• pregnancy;
• impossibility to perform the required diagnostic workup.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
SMAS patients	Duodenojejunostomy	-

Primary Outcome Measures

Name	Time	Method
Need for medical treatment	47 months (IQR 34-72)	PPIs, prokinetic drugs
Symptom score	47 months (IQR 34-72)	Severity (0-6) + frequency (0-5) x 5 symptoms (abd pain, nausea, vomiting, reflux, bloating)
BMI	47 months (IQR 34-72)	Body mass index

Trial Locations

Locations (1)

General Surgery Unit; 🇮🇹 Padova, PD, Italy