Metformin in the management of gestational diabetes mellitus
Not Applicable
- Conditions
- Gestational Diabetes Mellitus.Diabetes mellitus arising in pregnancy
- Registration Number
- IRCT201105075591N2
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 160
Inclusion Criteria
1 - 18 to 40 years old pregnant women 2 - Singleton Pregnancy 3 - gestational age between 20 to 34 weeks (based on reliable LMP or ultrasound before 20 weeks of gestation) 3 - Diagnosis of GDM based on 2 or more abnormal values in GTT as per Carpenter and Coustan's criterion. Exclusion criteria: 1 - Systemic underlying disease (cardiovascular, pulmonary, renal , liver and autoimmune) 2 - Substance Abuse 3- Overt diabetes mellitus (except previous history of GDM)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma glucose. Timepoint: twice a week. Method of measurement: laboratory (mg/dl).
- Secondary Outcome Measures
Name Time Method Preeclampsia. Timepoint: Antenatal and postpartum. Method of measurement: blood pressure (mmhg),proteinuria (mg/dl).;Preterm delivery. Timepoint: postnatal. Method of measurement: gestational age (week).;Cesarean section. Timepoint: tim of delivery. Method of measurement: mode of delivery.;Perinatal mortality. Timepoint: antenatal,neonatal period. Method of measurement: IUFD,Still birth,neonatal death.;Macrosomia. Timepoint: birth time. Method of measurement: birth weight(kg).;Hypoglycemia. Timepoint: 1st 24hr after birth. Method of measurement: laboratory (mg/dl).;NICU admission. Timepoint: neonatal period. Method of measurement: day.