Influence of Neuromuscular Block on Mask Ventilation

Not Applicable

Completed

• Conditions: Effect of a Neuromuscular Block on Ventilation
• Interventions: Drug: rocuronium

• Registration Number: NCT01849211
• Lead Sponsor: Kreiskrankenhaus Dormagen

Brief Summary

Difficult mask ventilation might lead to a life-threatening situation, if endotracheal intubation is also impossible and neuromuscular blocking agents (NMBA) inhibit spontaneous ventilation. However, controversies exist if NMBA improve or impede face mask ventilation. Therefore, the effect of NMBAs on mask ventilation is assessed in patients with predictors for difficult face mask ventilation.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-04
• Study First Submitted: 2013-04-25
• Study First Submitted QC: 2013-05-07
• Study First Posted: 2013-05-08
• Primary Completion: 2017-04
• Status Verified: 2018-03
• Study Completion: 2018-03
• Last Update Submitted: 2020-02-19
• Last Update Posted: 2020-02-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Patients with risk factors for difficult face mask ventilation
• Patients scheduled for general anaesthesia with endotracheal intubation

Exclusion Criteria

• Increased Risk for pulmonary aspiration
• scheduled for awake fiberoptic intubation
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
neuromuscular block	rocuronium	-

Primary Outcome Measures

Name	Time	Method
minute volume	15 min (from Induction of anaesthesia until onset of NMBA )

Secondary Outcome Measures

Name	Time	Method
incidence of difficult mask ventilation - tidal volume < 150 ml	15 min

Trial Locations

Locations (1)

KKH Dormagen; 🇩🇪 Dormagen, Germany