Comparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung Cancer
- Conditions
- Lung Cancer
- Interventions
- Procedure: lobectomyProcedure: segmentectomy or wedge resection
- Registration Number
- NCT00499330
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Brief Summary
RATIONALE: Wedge resection or segmentectomy may be less invasive types of surgery than lobectomy for non-small cell lung cancer and may have fewer side effects and improve recovery. It is not yet known whether wedge resection or segmentectomy are more effective than lobectomy in treating stage IA non-small cell lung cancer.
PURPOSE: This randomized phase III trial is studying different types of surgery to compare how well they work in treating patients with stage IA non-small cell lung cancer.
- Detailed Description
OUTLINE: This is a multicenter, randomized study. Patients are stratified according to tumor size (\< 1 cm vs 1-1.5 cm vs \> 1.5-2.0 cm) (based on the maximum dimension determined from the preoperative CT scan), histology (squamous cell carcinoma vs adenocarcinoma vs other), and smoking status (never smoked \[smoked \< 100 cigarettes over lifetime\] vs former smoker \[smoked \> 100 cigarettes AND quit ≥ 1 year ago\] vs current smoker \[quit \< 1 year ago or currently smokes\]). Patients are randomized to 1 of 2 treatment arms. For more information, please see the Arms section.
Primary Objective:
To determine whether DFS after sublobar resection (segmentectomy or wedge) is non-inferior to that after lobectomy in patients with small peripheral (≤ 2 cm) NSCLC.
Secondary Objectives:
1. To determine whether overall survival (OS) (after sublobar resection) is non-inferior to that after lobectomy.
2. To determine the rates of loco-regional and systemic recurrence (exclusive of second primaries) after lobar and sublobar resection.
3. To determine the difference between the two arms of the study in pulmonary function as determined by expiratory flow rates measured at 6 months post-operatively.
4. Imaging Substudy: To explore the relationship between characteristics of the primary lung cancer, as revealed by pre-operative CT and PET imaging, and outcomes; a determination of the false-negative rate of the pre-operative PET scan for identification of involved hilarand mediastinal lymph nodes; and an assessment of the utility of annual follow-up CT imaging after surgical resection of small stage IA NSCLC.
After completion of study treatment, patients are followed up every 6 months for 2 years and then annually for 5 years.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 701
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Arm A lobectomy Patients undergo a standard operation for lung cancer called a lobectomy. Arm B segmentectomy or wedge resection Patents undergo a limited resection (segentectomy or wedge resection), which a smaller portion of the lung is removed.
- Primary Outcome Measures
Name Time Method disease-free survival Up to 7 years
- Secondary Outcome Measures
Name Time Method rate of loco-regional and systemic recurrence Up to 7 years pulmonary function as measured by expiratory flow rate 6 months postoperatively at 6 months overall survival Up to 7 years
Trial Locations
- Locations (385)
Saint Mary Corwin Medical Center
🇺🇸Pueblo, Colorado, United States
Saint Vincent's Hospital
🇦🇺Fitzroy, Victoria, Australia
Allegheny General Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
UPMC-Magee Womens Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
UPMC-Saint Margaret
🇺🇸Pittsburgh, Pennsylvania, United States
West Penn Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
Columbus NCI Community Oncology Research Program
🇺🇸Columbus, Ohio, United States
M D Anderson Cancer Center
🇺🇸Houston, Texas, United States
Minor and James Medical PLLC
🇺🇸Seattle, Washington, United States
Pacific Gynecology Specialists
🇺🇸Seattle, Washington, United States
Fred Hutchinson Cancer Research Center
🇺🇸Seattle, Washington, United States
University of Washington Medical Center
🇺🇸Seattle, Washington, United States
Indiana University/Melvin and Bren Simon Cancer Center
🇺🇸Indianapolis, Indiana, United States
TriHealth Cancer Institute-Westside
🇺🇸Cincinnati, Ohio, United States
Anchorage Radiation Therapy Center
🇺🇸Anchorage, Alaska, United States
Alaska Breast Care and Surgery LLC
🇺🇸Anchorage, Alaska, United States
Alaska Oncology and Hematology LLC
🇺🇸Anchorage, Alaska, United States
Alaska Regional Hospital
🇺🇸Anchorage, Alaska, United States
Anchorage Oncology Centre
🇺🇸Anchorage, Alaska, United States
Katmai Oncology Group
🇺🇸Anchorage, Alaska, United States
Mayo Clinic in Arizona
🇺🇸Scottsdale, Arizona, United States
University of Arkansas for Medical Sciences
🇺🇸Little Rock, Arkansas, United States
Mercy Cancer Center-Hot Springs
🇺🇸Hot Springs, Arkansas, United States
Highlands Oncology Group-Rogers
🇺🇸Rogers, Arkansas, United States
University of California San Diego
🇺🇸San Diego, California, United States
Penrose-Saint Francis Healthcare
🇺🇸Colorado Springs, Colorado, United States
Longmont United Hospital
🇺🇸Longmont, Colorado, United States
Saint Vincent's Medical Center
🇺🇸Bridgeport, Connecticut, United States
Smilow Cancer Hospital Care Center at Saint Francis
🇺🇸Hartford, Connecticut, United States
Stamford Hospital/Bennett Cancer Center
🇺🇸Stamford, Connecticut, United States
Beebe Medical Center
🇺🇸Lewes, Delaware, United States
Delaware Clinical and Laboratory Physicians PA
🇺🇸Newark, Delaware, United States
Christiana Gynecologic Oncology LLC
🇺🇸Newark, Delaware, United States
Medical Oncology Hematology Consultants PA
🇺🇸Newark, Delaware, United States
Regional Hematology and Oncology PA
🇺🇸Newark, Delaware, United States
Christiana Care Health System-Christiana Hospital
🇺🇸Newark, Delaware, United States
Beebe Health Campus
🇺🇸Rehoboth Beach, Delaware, United States
Christiana Care Health System-Wilmington Hospital
🇺🇸Wilmington, Delaware, United States
Boca Raton Regional Hospital
🇺🇸Boca Raton, Florida, United States
Mayo Clinic in Florida
🇺🇸Jacksonville, Florida, United States
Saint Alphonsus Cancer Care Center-Caldwell
🇺🇸Caldwell, Idaho, United States
Kootenai Medical Center
🇺🇸Coeur d'Alene, Idaho, United States
Walter Knox Memorial Hospital
🇺🇸Emmett, Idaho, United States
Saint Luke's Mountain States Tumor Institute - Fruitland
🇺🇸Fruitland, Idaho, United States
Saint Joseph Regional Medical Center
🇺🇸Lewiston, Idaho, United States
Idaho Urologic Institute-Meridian
🇺🇸Meridian, Idaho, United States
Saint Luke's Mountain States Tumor Institute - Meridian
🇺🇸Meridian, Idaho, United States
Saint Luke's Mountain States Tumor Institute - Nampa
🇺🇸Nampa, Idaho, United States
Kootenai Cancer Center
🇺🇸Post Falls, Idaho, United States
Kootenai Cancer Clinic
🇺🇸Sandpoint, Idaho, United States
Olathe Cancer Center
🇺🇸Olathe, Kansas, United States
Menorah Medical Center
🇺🇸Overland Park, Kansas, United States
Anne Arundel Medical Center
🇺🇸Annapolis, Maryland, United States
University of Maryland/Greenebaum Cancer Center
🇺🇸Baltimore, Maryland, United States
Union Hospital of Cecil County
🇺🇸Elkton, Maryland, United States
Holy Cross Hospital
🇺🇸Silver Spring, Maryland, United States
Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States
Boston Medical Center
🇺🇸Boston, Massachusetts, United States
Dana-Farber Cancer Institute
🇺🇸Boston, Massachusetts, United States
D'Amour Center for Cancer Care
🇺🇸Springfield, Massachusetts, United States
University of Massachusetts Memorial Health Care
🇺🇸Worcester, Massachusetts, United States
Saint Joseph Mercy Brighton
🇺🇸Brighton, Michigan, United States
IHA Hematology Oncology Consultants-Canton
🇺🇸Canton, Michigan, United States
IHA Hematology Oncology Consultants-Chelsea
🇺🇸Chelsea, Michigan, United States
Hematology Oncology Consultants-Clarkston
🇺🇸Clarkston, Michigan, United States
Saint Joseph Mercy Chelsea
🇺🇸Chelsea, Michigan, United States
Newland Medical Associates-Clarkston
🇺🇸Clarkston, Michigan, United States
Genesys Hurley Cancer Institute
🇺🇸Flint, Michigan, United States
Great Lakes Cancer Management Specialists-Doctors Park
🇺🇸East China Township, Michigan, United States
Genesys Regional Medical Center-West Flint Campus
🇺🇸Flint, Michigan, United States
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
🇺🇸Grosse Pointe Woods, Michigan, United States
Lymphoma Clinic of Michigan
🇺🇸Grosse Pointe Woods, Michigan, United States
Allegiance Health
🇺🇸Jackson, Michigan, United States
Sparrow Hospital
🇺🇸Lansing, Michigan, United States
Hope Cancer Clinic
🇺🇸Livonia, Michigan, United States
Saint Mary Mercy Hospital
🇺🇸Livonia, Michigan, United States
Saint Mary's of Michigan
🇺🇸Saginaw, Michigan, United States
Michigan Breast Specialists-Macomb Township
🇺🇸Macomb, Michigan, United States
21st Century Oncology-Pontiac
🇺🇸Pontiac, Michigan, United States
Newland Medical Associates-Pontiac
🇺🇸Pontiac, Michigan, United States
Saint Joseph Mercy Oakland
🇺🇸Pontiac, Michigan, United States
Lake Huron Medical Center
🇺🇸Port Huron, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC
🇺🇸Saginaw, Michigan, United States
Bhadresh Nayak MD PC-Sterling Heights
🇺🇸Sterling Heights, Michigan, United States
Great Lakes Cancer Management Specialists-Macomb Professional Building
🇺🇸Warren, Michigan, United States
Michigan Breast Specialists-Warren
🇺🇸Warren, Michigan, United States
Macomb Hematology Oncology PC
🇺🇸Warren, Michigan, United States
Saint John Macomb-Oakland Hospital
🇺🇸Warren, Michigan, United States
Huron Gastroenterology PC
🇺🇸Ypsilanti, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch
🇺🇸West Branch, Michigan, United States
IHA Hematology Oncology Consultants-Ann Arbor
🇺🇸Ypsilanti, Michigan, United States
Saint Joseph Oncology Inc
🇺🇸Saint Joseph, Missouri, United States
Billings Clinic Cancer Center
🇺🇸Billings, Montana, United States
Saint Vincent Healthcare
🇺🇸Billings, Montana, United States
Big Sky Oncology
🇺🇸Great Falls, Montana, United States
Saint James Community Hospital and Cancer Treatment Center
🇺🇸Butte, Montana, United States
Benefis Healthcare- Sletten Cancer Institute
🇺🇸Great Falls, Montana, United States
Community Medical Hospital
🇺🇸Missoula, Montana, United States
Kalispell Regional Medical Center
🇺🇸Kalispell, Montana, United States
CHI Health Saint Francis
🇺🇸Grand Island, Nebraska, United States
Heartland Hematology and Oncology
🇺🇸Kearney, Nebraska, United States
CHI Health Good Samaritan
🇺🇸Kearney, Nebraska, United States
Saint Elizabeth Regional Medical Center
🇺🇸Lincoln, Nebraska, United States
Memorial Sloan Kettering Cancer Center at Basking Ridge
🇺🇸Basking Ridge, New Jersey, United States
John F Kennedy Medical Center
🇺🇸Edison, New Jersey, United States
Valley Health System-Hematology/Oncology
🇺🇸Westwood, New Jersey, United States
TriHealth Cancer Institute-Anderson
🇺🇸Cincinnati, Ohio, United States
Saint Alphonsus Medical Center-Baker City
🇺🇸Baker City, Oregon, United States
Bay Area Hospital
🇺🇸Coos Bay, Oregon, United States
Providence Willamette Falls Medical Center
🇺🇸Oregon City, Oregon, United States
Geisinger Medical Center
🇺🇸Danville, Pennsylvania, United States
Forbes Hospital
🇺🇸Monroeville, Pennsylvania, United States
UPMC-Presbyterian Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
Greenville Health System Cancer Institute-Easley
🇺🇸Easley, South Carolina, United States
Greenville Health System Cancer Institute-Butternut
🇺🇸Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Seneca
🇺🇸Seneca, South Carolina, United States
Memorial Hospital
🇺🇸Chattanooga, Tennessee, United States
Pulmonary Medicine Center of Chattanooga-Hixson
🇺🇸Hixson, Tennessee, United States
Memorial GYN Plus
🇺🇸Ooltewah, Tennessee, United States
UT Southwestern/Simmons Cancer Center-Dallas
🇺🇸Dallas, Texas, United States
American Fork Hospital / Huntsman Intermountain Cancer Center
🇺🇸American Fork, Utah, United States
Virginia Oncology Associates - Lake Wright
🇺🇸Norfolk, Virginia, United States
Providence Regional Cancer Partnership
🇺🇸Everett, Washington, United States
Harborview Medical Center
🇺🇸Seattle, Washington, United States
Virginia Mason Medical Center
🇺🇸Seattle, Washington, United States
Saint Joseph's Healthcare Charlton Campus
🇨🇦Hamilton, Ontario, Canada
University Health Network-Princess Margaret Hospital
🇨🇦Toronto, Ontario, Canada
CIUSSSEMTL-Hopital Maisonneuve-Rosemont
🇨🇦Montreal, Quebec, Canada
CHUM - Hopital Notre-Dame
🇨🇦Montreal, Quebec, Canada
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
🇨🇦Sherbrooke, Quebec, Canada
University Institute of Cardiology and Pneumology of Quebec (Laval Hospital)
🇨🇦Quebec, Canada
UC Irvine Health/Chao Family Comprehensive Cancer Center
🇺🇸Orange, California, United States
Veterans Administration Long Beach Medical Center
🇺🇸Long Beach, California, United States
Henry Ford Hospital
🇺🇸Detroit, Michigan, United States
Kaiser Permanente-Riverside
🇺🇸Riverside, California, United States
Saint John Hospital and Medical Center
🇺🇸Detroit, Michigan, United States
Mercy Medical Center
🇺🇸Canton, Ohio, United States
Emory University Hospital Midtown
🇺🇸Atlanta, Georgia, United States
Emory University/Winship Cancer Institute
🇺🇸Atlanta, Georgia, United States
Atlanta VA Medical Center
🇺🇸Decatur, Georgia, United States
Memorial University Medical Center
🇺🇸Savannah, Georgia, United States
University of Chicago Comprehensive Cancer Center
🇺🇸Chicago, Illinois, United States
Saint John's Hospital
🇺🇸Springfield, Illinois, United States
Southern Illinois University School of Medicine
🇺🇸Springfield, Illinois, United States
Richard L. Roudebush Veterans Affairs Medical Center
🇺🇸Indianapolis, Indiana, United States
Littleton Adventist Hospital
🇺🇸Littleton, Colorado, United States
University of Kansas Cancer Center
🇺🇸Kansas City, Kansas, United States
Saint Anthony Hospital
🇺🇸Lakewood, Colorado, United States
Rocky Mountain Cancer Centers-Penrose
🇺🇸Colorado Springs, Colorado, United States
Saint Luke's South Hospital
🇺🇸Overland Park, Kansas, United States
Rocky Mountain Cancer Centers-Thornton
🇺🇸Thornton, Colorado, United States
Mountain Blue Cancer Care Center
🇺🇸Golden, Colorado, United States
Southwest Oncology PC
🇺🇸Durango, Colorado, United States
Rocky Mountain Cancer Centers-Longmont
🇺🇸Longmont, Colorado, United States
Rocky Mountain Cancer Centers - Pueblo
🇺🇸Pueblo, Colorado, United States
Rocky Mountain Cancer Centers-Lakewood
🇺🇸Lakewood, Colorado, United States
Welch Cancer Center
🇺🇸Sheridan, Wyoming, United States
Memorial Hospital Colorado Springs
🇺🇸Colorado Springs, Colorado, United States
Parker Adventist Hospital
🇺🇸Parker, Colorado, United States
Rocky Mountain Cancer Centers-Parker
🇺🇸Parker, Colorado, United States
Billings Clinic-Cody
🇺🇸Cody, Wyoming, United States
Shawnee Mission Medical Center-KCCC
🇺🇸Shawnee Mission, Kansas, United States
Big Horn Basin Cancer Center
🇺🇸Cody, Wyoming, United States
Sidney and Lois Eskenazi Hospital
🇺🇸Indianapolis, Indiana, United States
Memorial Regional Cancer Center Day Road
🇺🇸Mishawaka, Indiana, United States
Memorial Hospital of South Bend
🇺🇸South Bend, Indiana, United States
Medical Oncology and Hematology Associates-West Des Moines
🇺🇸Clive, Iowa, United States
Mercy Cancer Center-West Lakes
🇺🇸Clive, Iowa, United States
Alegent Health Mercy Hospital
🇺🇸Council Bluffs, Iowa, United States
Greater Regional Medical Center
🇺🇸Creston, Iowa, United States
Mercy Medical Center-West Lakes
🇺🇸West Des Moines, Iowa, United States
Flaget Memorial Hospital
🇺🇸Bardstown, Kentucky, United States
Commonwealth Cancer Center-Corbin
🇺🇸Corbin, Kentucky, United States
Jewish Hospital Medical Center South
🇺🇸Shepherdsville, Kentucky, United States
Southeast Missouri Hospital
🇺🇸Cape Girardeau, Missouri, United States
Alaska Women's Cancer Care
🇺🇸Anchorage, Alaska, United States
Saint Joseph Mercy Canton Health Center
🇺🇸Canton, Michigan, United States
Nanticoke Memorial Hospital
🇺🇸Seaford, Delaware, United States
Saint Alphonsus Medical Center-Nampa
🇺🇸Nampa, Idaho, United States
Anchorage Associates in Radiation Medicine
🇺🇸Anchorage, Alaska, United States
Providence Alaska Medical Center
🇺🇸Anchorage, Alaska, United States
Michigan Breast Specialists-Grosse Pointe Woods
🇺🇸Grosse Pointe Woods, Michigan, United States
Valley Hospital
🇺🇸Ridgewood, New Jersey, United States
Jersey Shore Medical Center
🇺🇸Neptune, New Jersey, United States
Genesee Hematology Oncology PC
🇺🇸Flint, Michigan, United States
Saint Luke's Mountain States Tumor Institute
🇺🇸Boise, Idaho, United States
The University of Arizona Medical Center-University Campus
🇺🇸Tucson, Arizona, United States
IHA Hematology Oncology Consultants-Brighton
🇺🇸Brighton, Michigan, United States
Beaumont Hospital-Dearborn
🇺🇸Dearborn, Michigan, United States
Saint Luke's Mountain States Tumor Institute-Twin Falls
🇺🇸Twin Falls, Idaho, United States
Berkshire Hematology Oncology PC
🇺🇸Pittsfield, Massachusetts, United States
Ocean Medical Center
🇺🇸Brick, New Jersey, United States
Genesee Cancer and Blood Disease Treatment Center
🇺🇸Flint, Michigan, United States
Saint Patrick Hospital - Community Hospital
🇺🇸Missoula, Montana, United States
Hope Cancer Center
🇺🇸Pontiac, Michigan, United States
Cooper Hospital University Medical Center
🇺🇸Camden, New Jersey, United States
Portneuf Medical Center
🇺🇸Pocatello, Idaho, United States
Massachusetts General Hospital Cancer Center
🇺🇸Boston, Massachusetts, United States
Hematology Oncology Associates East PC
🇺🇸Macomb, Michigan, United States
Helen F Graham Cancer Center
🇺🇸Newark, Delaware, United States
Hurley Medical Center
🇺🇸Flint, Michigan, United States
Bozeman Deaconess Hospital
🇺🇸Bozeman, Montana, United States
Saint Alphonsus Cancer Care Center-Boise
🇺🇸Boise, Idaho, United States
Great Lakes Cancer Management Specialists-Rochester Hills
🇺🇸Rochester Hills, Michigan, United States
Clackamas Radiation Oncology Center
🇺🇸Clackamas, Oregon, United States
Fox Valley Surgical Associates Limited
🇺🇸Appleton, Wisconsin, United States
Saint Joseph's Health Centre
🇨🇦Toronto, Ontario, Canada
QEII Health Sciences Centre/Capital District Health Authority
🇨🇦Halifax, Nova Scotia, Canada
Saint Peter's Community Hospital
🇺🇸Helena, Montana, United States
Surrey Memorial Hospital
🇨🇦Surrey, British Columbia, Canada
Genesys Regional Medical Center
🇺🇸Grand Blanc, Michigan, United States
Midlands Community Hospital
🇺🇸Papillion, Nebraska, United States
Providence Milwaukie Hospital
🇺🇸Milwaukie, Oregon, United States
Great Falls Clinic
🇺🇸Great Falls, Montana, United States
Central Vermont Medical Center/National Life Cancer Treatment
🇺🇸Berlin, Vermont, United States
University of Tennessee - Knoxville
🇺🇸Knoxville, Tennessee, United States
Greenville Health System Cancer Institute-Spartanburg
🇺🇸Spartanburg, South Carolina, United States
Ottawa Hospital and Cancer Center-General Campus
🇨🇦Ottawa, Ontario, Canada
Riverview Medical Center/Booker Cancer Center
🇺🇸Red Bank, New Jersey, United States
Saint Alphonsus Medical Center-Ontario
🇺🇸Ontario, Oregon, United States
Providence Newberg Medical Center
🇺🇸Newberg, Oregon, United States
The Moncton Hospital
🇨🇦Moncton, New Brunswick, Canada
University of Vermont College of Medicine
🇺🇸Burlington, Vermont, United States
The Valley Hospital-Luckow Pavilion
🇺🇸Paramus, New Jersey, United States
Saint Charles Health System
🇺🇸Bend, Oregon, United States
Providence Oncology and Hematology Care Southeast
🇺🇸Clackamas, Oregon, United States
Greenville Memorial Hospital
🇺🇸Greenville, South Carolina, United States
London Regional Cancer Program
🇨🇦London, Ontario, Canada
Mercy Medical Center - Des Moines
🇺🇸Des Moines, Iowa, United States
Saint Luke's East - Lee's Summit
🇺🇸Lee's Summit, Missouri, United States
Liberty Radiation Oncology Center
🇺🇸Liberty, Missouri, United States
Heartland Regional Medical Center
🇺🇸Saint Joseph, Missouri, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center
🇺🇸Burbank, California, United States
Mercy San Juan Medical Center
🇺🇸Carmichael, California, United States
Saint Jude Medical Center
🇺🇸Fullerton, California, United States
Loma Linda University Medical Center
🇺🇸Loma Linda, California, United States
Veterans Affairs Loma Linda Healthcare System
🇺🇸Loma Linda, California, United States
Washington University School of Medicine
🇺🇸Saint Louis, Missouri, United States
Christian Hospital
🇺🇸Saint Louis, Missouri, United States
Roswell Park Cancer Institute
🇺🇸Buffalo, New York, United States
Memorial Sloan Kettering Commack
🇺🇸Commack, New York, United States
Hematology Oncology Associates of Central New York-East Syracuse
🇺🇸East Syracuse, New York, United States
The New York Hospital Medical Center of Queens
🇺🇸Flushing, New York, United States
Memorial Sloan-Kettering Cancer Center West Harrison
🇺🇸Harrison, New York, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone
🇺🇸New York, New York, United States
Weill Medical College of Cornell University
🇺🇸New York, New York, United States
Memorial Sloan-Kettering Cancer Center
🇺🇸New York, New York, United States
Memorial Sloan Kettering Rockville Centre
🇺🇸Rockville Centre, New York, United States
State University of New York Upstate Medical University
🇺🇸Syracuse, New York, United States
Southeastern Medical Oncology Center-Clinton
🇺🇸Clinton, North Carolina, United States
Asheville VA Medical Center
🇺🇸Asheville, North Carolina, United States
Duke University Medical Center
🇺🇸Durham, North Carolina, United States
Southeastern Medical Oncology Center-Goldsboro
🇺🇸Goldsboro, North Carolina, United States
Southeastern Medical Oncology Center-Jacksonville
🇺🇸Jacksonville, North Carolina, United States
Good Samaritan Hospital - Cincinnati
🇺🇸Cincinnati, Ohio, United States
Bethesda North Hospital
🇺🇸Cincinnati, Ohio, United States
Southeastern Medical Oncology Center-Wilson
🇺🇸Wilson, North Carolina, United States
Mary Rutan Hospital
🇺🇸Bellefontaine, Ohio, United States
Adena Regional Medical Center
🇺🇸Chillicothe, Ohio, United States
Ohio State University Comprehensive Cancer Center
🇺🇸Columbus, Ohio, United States
Riverside Methodist Hospital
🇺🇸Columbus, Ohio, United States
Grant Medical Center
🇺🇸Columbus, Ohio, United States
The Mark H Zangmeister Center
🇺🇸Columbus, Ohio, United States
Mount Carmel Health Center West
🇺🇸Columbus, Ohio, United States
Licking Memorial Hospital
🇺🇸Newark, Ohio, United States
Fairfield Medical Center
🇺🇸Lancaster, Ohio, United States
Doctors Hospital
🇺🇸Columbus, Ohio, United States
Grady Memorial Hospital
🇺🇸Delaware, Ohio, United States
Marietta Memorial Hospital
🇺🇸Marietta, Ohio, United States
Knox Community Hospital
🇺🇸Mount Vernon, Ohio, United States
Tod Children's Hospital - Forum Health
🇺🇸Youngstown, Ohio, United States
Lehigh Valley Hospital-Cedar Crest
🇺🇸Allentown, Pennsylvania, United States
Armstrong Center for Medicine and Health
🇺🇸Kittanning, Pennsylvania, United States
University of Oklahoma Health Sciences Center
🇺🇸Oklahoma City, Oklahoma, United States
Lehigh Valley Hospital - Muhlenberg
🇺🇸Bethlehem, Pennsylvania, United States
Springfield Regional Medical Center
🇺🇸Springfield, Ohio, United States
Saint Ann's Hospital
🇺🇸Westerville, Ohio, United States
Genesis Healthcare System Cancer Care Center
🇺🇸Zanesville, Ohio, United States
Southern Ohio Medical Center
🇺🇸Portsmouth, Ohio, United States
Geisinger Medical Oncology-Lewisburg
🇺🇸Lewisburg, Pennsylvania, United States
Allegheny Valley Hospital
🇺🇸Natrona Heights, Pennsylvania, United States
Jameson Health System North Campus
🇺🇸New Castle, Pennsylvania, United States
Thomas Jefferson University Hospital
🇺🇸Philadelphia, Pennsylvania, United States
Fox Chase Cancer Center
🇺🇸Philadelphia, Pennsylvania, United States
University of Pittsburgh Cancer Institute (UPCI)
🇺🇸Pittsburgh, Pennsylvania, United States
UPMC-Shadyside Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
Guthrie Medical Group PC-Robert Packer Hospital
🇺🇸Sayre, Pennsylvania, United States
UPMC-Passavant Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
Geisinger Medical Oncology-Pottsville
🇺🇸Pottsville, Pennsylvania, United States
Penn State Health Saint Joseph Medical Center
🇺🇸Reading, Pennsylvania, United States
Saint Joseph Regional Cancer Center
🇺🇸Bryan, Texas, United States
Medical City Dallas Hospital
🇺🇸Dallas, Texas, United States
University of Virginia Cancer Center
🇺🇸Charlottesville, Virginia, United States
Mary Washington Hospital
🇺🇸Fredericksburg, Virginia, United States
Sentara Norfolk General Hospital
🇺🇸Norfolk, Virginia, United States
Sentara Cancer Institute at Sentara CarePlex Hospital
🇺🇸Hampton, Virginia, United States
Virginia Oncology Associates-Hampton
🇺🇸Hampton, Virginia, United States
Sentara Williamsburg Regional Medical Center
🇺🇸Williamsburg, Virginia, United States
Providence Regional Cancer System-Aberdeen
🇺🇸Aberdeen, Washington, United States
Cancer Care Center at Island Hospital
🇺🇸Anacortes, Washington, United States
Overlake Hospital Medical Center
🇺🇸Bellevue, Washington, United States
MultiCare Auburn Medical Center
🇺🇸Auburn, Washington, United States
Swedish Cancer Institute-Eastside Oncology Hematology
🇺🇸Bellevue, Washington, United States
PeaceHealth Saint Joseph Medical Center
🇺🇸Bellingham, Washington, United States
Harrison HealthPartners Hematology and Oncology-Bremerton
🇺🇸Bremerton, Washington, United States
Harrison Medical Center
🇺🇸Bremerton, Washington, United States
Swedish Medical Center-Edmonds
🇺🇸Edmonds, Washington, United States
Highline Medical Center-Main Campus
🇺🇸Burien, Washington, United States
Saint Elizabeth Hospital
🇺🇸Enumclaw, Washington, United States
Providence Regional Cancer System-Centralia
🇺🇸Centralia, Washington, United States
Saint Francis Hospital
🇺🇸Federal Way, Washington, United States
Swedish Cancer Institute-Issaquah
🇺🇸Issaquah, Washington, United States
Kadlec Clinic Hematology and Oncology
🇺🇸Kennewick, Washington, United States
Seattle Cancer Care Alliance at EvergreenHealth
🇺🇸Kirkland, Washington, United States
Saint Clare Hospital
🇺🇸Lakewood, Washington, United States
Providence Regional Cancer System-Lacey
🇺🇸Lacey, Washington, United States
Skagit Valley Hospital
🇺🇸Mount Vernon, Washington, United States
PeaceHealth Saint John Medical Center
🇺🇸Longview, Washington, United States
Providence - Saint Peter Hospital
🇺🇸Olympia, Washington, United States
MultiCare Good Samaritan Hospital
🇺🇸Puyallup, Washington, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo
🇺🇸Poulsbo, Washington, United States
Swedish Medical Center-Ballard Campus
🇺🇸Seattle, Washington, United States
Group Health Cooperative-Seattle
🇺🇸Seattle, Washington, United States
Swedish Medical Center-First Hill
🇺🇸Seattle, Washington, United States
United General Hospital
🇺🇸Sedro-Woolley, Washington, United States
Cancer Care Northwest - Spokane South
🇺🇸Spokane, Washington, United States
Providence Regional Cancer System-Shelton
🇺🇸Shelton, Washington, United States
Rockwood Cancer Treatment Center-DHEC-Downtown
🇺🇸Spokane, Washington, United States
MultiCare Tacoma General Hospital
🇺🇸Tacoma, Washington, United States
Northwest Medical Specialties PLLC
🇺🇸Tacoma, Washington, United States
Evergreen Hematology and Oncology PS
🇺🇸Spokane, Washington, United States
Rockwood North Cancer Treatment Center
🇺🇸Spokane, Washington, United States
Rockwood Clinic
🇺🇸Spokane, Washington, United States
Franciscan Research Center-Northwest Medical Plaza
🇺🇸Tacoma, Washington, United States
MultiCare Allenmore Hospital
🇺🇸Tacoma, Washington, United States
Saint Joseph Medical Center
🇺🇸Tacoma, Washington, United States
PeaceHealth Southwest Medical Center
🇺🇸Vancouver, Washington, United States
Compass Oncology Vancouver
🇺🇸Vancouver, Washington, United States
Wenatchee Valley Hospital and Clinics
🇺🇸Wenatchee, Washington, United States
Providence Saint Mary Regional Cancer Center
🇺🇸Walla Walla, Washington, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
🇺🇸Yakima, Washington, United States
Providence Regional Cancer System-Yelm
🇺🇸Yelm, Washington, United States
University of Alabama at Birmingham Cancer Center
🇺🇸Birmingham, Alabama, United States
Porter Adventist Hospital
🇺🇸Denver, Colorado, United States
University of Colorado
🇺🇸Denver, Colorado, United States
Providence Portland Medical Center
🇺🇸Portland, Oregon, United States
Providence Saint Vincent Medical Center
🇺🇸Portland, Oregon, United States
Portland Veterans Administration Medical Center
🇺🇸Portland, Oregon, United States
Hemotology and Oncology Consultants PC
🇺🇸Omaha, Nebraska, United States
Creighton University Medical Center
🇺🇸Omaha, Nebraska, United States
Mayo Clinic
🇺🇸Rochester, Minnesota, United States
Alegent Health Immanuel Medical Center
🇺🇸Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center
🇺🇸Omaha, Nebraska, United States
Alegent Health Lakeside Hospital
🇺🇸Omaha, Nebraska, United States
University of Nebraska Medical Center
🇺🇸Omaha, Nebraska, United States
Froedtert and the Medical College of Wisconsin
🇺🇸Milwaukee, Wisconsin, United States
University of Colorado Cancer Center - Anschutz Cancer Pavilion
🇺🇸Aurora, Colorado, United States
Upper Chesapeake Medical Center
🇺🇸Bel Air, Maryland, United States
University of California Davis Comprehensive Cancer Center
🇺🇸Sacramento, California, United States
Saint Joseph Mercy Hospital
🇺🇸Ann Arbor, Michigan, United States
Michigan Cancer Research Consortium NCORP
🇺🇸Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center
🇺🇸Ann Arbor, Michigan, United States
Jewish Hospital
🇺🇸Louisville, Kentucky, United States
Saints Mary and Elizabeth Hospital
🇺🇸Louisville, Kentucky, United States
Jewish Hospital Medical Center Northeast
🇺🇸Louisville, Kentucky, United States
Saint Joseph Health Center
🇺🇸Kansas City, Missouri, United States
Heartland Hematology and Oncology Associates Incorporated
🇺🇸Kansas City, Missouri, United States
Medical University of South Carolina
🇺🇸Charleston, South Carolina, United States
North Kansas City Hospital
🇺🇸Kansas City, Missouri, United States
Research Medical Center
🇺🇸Kansas City, Missouri, United States
Truman Medical Center
🇺🇸Kansas City, Missouri, United States
Saint Luke's Hospital of Kansas City
🇺🇸Kansas City, Missouri, United States
Medical Oncology and Hematology Associates-Laurel
🇺🇸Des Moines, Iowa, United States
Saint Joseph Radiation Oncology Resource Center
🇺🇸Lexington, Kentucky, United States
Saint Joseph Hospital East
🇺🇸Lexington, Kentucky, United States
University of Kentucky/Markey Cancer Center
🇺🇸Lexington, Kentucky, United States
Ochsner Medical Center Jefferson
🇺🇸New Orleans, Louisiana, United States
Virginia Commonwealth University/Massey Cancer Center
🇺🇸Richmond, Virginia, United States
University of Wisconsin Hospital and Clinics
🇺🇸Madison, Wisconsin, United States
University of Rochester
🇺🇸Rochester, New York, United States
Wayne Memorial Hospital
🇺🇸Goldsboro, North Carolina, United States
Caro Cancer Center
🇺🇸Caro, Michigan, United States
Community Hospital of Anaconda
🇺🇸Anaconda, Montana, United States
Southern Ocean County Medical Center
🇺🇸Manahawkin, New Jersey, United States
Rockwood Clinic Cancer Treatment Center-Valley
🇺🇸Spokane Valley, Washington, United States