Evaluation of YKL-40 and LL-37 levels in saliva of children with Down syndrome: A cross sectional study.

This study is a cross sectional study, double blinded, single center trial comparing the levels of YKL-40 and LL-37 levels in the saliva of children with Down syndrome and healthy children in 8 to 15 years old children that will be conducted in India. This study will be carried over the period of six months, and the saliva sample collection will be done in Coachmans position. The samples will be stored in -80 degrees after centrifugation. After collection of all the samples they will be sent for ELISA running and the data will be subjected to the statistical analysis.