Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 Patients

Not Applicable

Completed

• Conditions: Diabetes Mellitus Type 1

• Registration Number: NCT02538120
• Lead Sponsor: University Hospital, Angers

Brief Summary

This study aims to see whether or not the diabetes 1 patients have a neurovascular microcirculatory dysfunction using various microvascular tests which have been previously validated.

Microvascular responses will be assessed by Laser Speckle Contrast Imaging and expressed in Laser Speckle Perfusion Units (LSPU).

Detailed Description

The investigators will compare microvascular responses between diabetes type 1 patients with matched control-subjects.

Study Timeline

• Study Start: 2012-05
• Status Verified: 2015-08
• Study First Submitted: 2015-08-14
• Study First Submitted QC: 2015-08-28
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Study First Posted: 2015-09-02
• Last Update Submitted: 2016-02-11
• Last Update Posted: 2016-02-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Diabetes type 1 patients
• Matched control-subjects

Exclusion Criteria

• Patients or subjects with anti-inflammatory drugs

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Neurovascular microcirculatory response	one day	Neurovascular response will be assessed by laser speckle contrast imaging using various microvascular tests such as deionized water iontophoresis, local heating test. Results will be explained in Laser Speckle Perfusion Units (LSPU)

Trial Locations

Locations (1)

University Hospital; 🇫🇷 Angers, France