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Clinical Trials/NCT04278911
NCT04278911
Unknown
N/A

Effect of Cognitive Impairment (CI) on Prognosis in the Elderly Patients With Acute Coronary Syndrome (ACS)

Beijing Friendship Hospital1 site in 1 country500 target enrollmentJanuary 1, 2020
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ConditionsAcute Coronary SyndromeCognitive ImpairmentElderly

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acute Coronary Syndrome
Sponsor
Beijing Friendship Hospital
Enrollment
500
Locations
1
Primary Endpoint
MACE (major adverse cardiovascular events)
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This study aims to investigate the incidence and characteristics of cognitive Impairment(CI) in the elderly patients with acute coronary syndrome (ACS), and to determine whether CI are predictive of the prognosis of major adverse cardiovascular events (MACE) and mortality.

Registry
clinicaltrials.gov
Start Date
January 1, 2020
End Date
June 30, 2022
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hongwei Li, MD

Prof.

Beijing Friendship Hospital

Eligibility Criteria

Inclusion Criteria

  • •Confirmed ACS diagnosis （include unstable angina, ST-segment elevation myocardial infarction and Non ST-segment elevation myocardial infarction）
  • •fulfilled MMSE or MoCA
  • •patients agreed and provided informed consent

Exclusion Criteria

  • •Type 2 myocardial infarction and Acute nonischemic myocardial injury
  • •past history of malignant tumors
  • •Past history of stroke or dementia
  • •Hepatic insufficiency (ALT\>8ULN or ALT\>3ULN and TBIL\>2ULN)
  • •Renal insufficiency (GFR\<15 ml/min/1.73m2)

Outcomes

Primary Outcomes

MACE (major adverse cardiovascular events)

Time Frame: 12 months

Myocardial infarction, revascularization, stroke, cardiac death, all cause of death

Secondary Outcomes

  • Cognitive level decline(12 months)

Study Sites (1)

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