Efficacy of Ultrasound-guided Transversalis Fascia Plane Block (TFPB) in Controlling Postoperative Pain After Transverse Incision in Gynecologic Surgery

Not Applicable

Active, not recruiting

• Conditions: Transversalis Fascia Plane Block; Gynecologic Surgical Procedures

• Registration Number: NCT06847022
• Lead Sponsor: Thammasat University

Brief Summary

Transversalis fascia plane block (TFPB) has been studied and has shown to be very effective in controlling postoperative pain after caesarean section but has not been studied in open gynecologic surgery with transverse incision. Inadequate pain control after open gynecologic surgery is associated with negative consequences such as chronic pelvic pain. We would like to study the efficacy of TFPB in controlling postoperative pain after open gynecologic surgery with transverse incision.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-11-04
• Status Verified: 2025-02
• Study First Submitted: 2025-02-16
• Study First Submitted QC: 2025-02-20
• Last Update Submitted: 2025-02-20
• Study First Posted: 2025-02-26
• Last Update Posted: 2025-02-26
• Primary Completion: 2025-04-30
• Study Completion: 2025-04-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 32

Inclusion Criteria

• Patients who undergoing open gynecologic surgery under general anesthesia
• Age 18 - 70 years
• ASA Physical status I-III
• Transverse incision

Exclusion Criteria

• Creatinine clearance is less than 30 ml/min
• Body weight < 50 kg
• Re-open surgery
• Persistent chronic pelvic pain
• Allergic to medications used in this study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Postoperative 24 hours morphine requirement	24 hours

Secondary Outcome Measures

Name	Time	Method
postoperative pain score	1 hour, 6 hours, 24 hours
Side effects from postoperative opioids	24 hours	nausea vomiting, itching, respiratory depression
Incidence of chronic pelvic pain	3 months

Trial Locations

Locations (1)

Department of Anesthesiology, Faculty of Medicine, Thammasat University; 🇹🇭 Pathum Thani, Thailand