Creation of a Biobank of Biological Samples From Fertile Men
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Fertility
- Sponsor
- IRCCS San Raffaele
- Enrollment
- 2000
- Locations
- 2
- Primary Endpoint
- Prognostic role of the biological material
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Collection and conservation of human biological material from fertile subjects, i.e. men with previous parenthood (normospermic men, natural fathers).
Detailed Description
The project aims to collect biological material derived both from surgical resections of the most common urological tumors and from peripheral blood or other biological fluids such as urine or seminal fluid when available. The objective of the study is to establish a biobank of human biological material, which will allow access to samples of extreme value for the pathophysiological study of the tumor, its origin, mechanisms and markers of progression, as well as the creation of this collection it will represent an extremely valuable tool for the study of individual response to therapies.
Investigators
Andrea Salonia
Professor
IRCCS San Raffaele
Eligibility Criteria
Inclusion Criteria
- •Normospermic male individuals
- •Naturally fertile male individuals
- •Male individuals \> 18 years
Exclusion Criteria
- •Non-normospermic male individuals
- •Male individuals who are not naturally fertile
- •Male individuals \< 18 years
Outcomes
Primary Outcomes
Prognostic role of the biological material
Time Frame: Baseline
Biological signature in fertile men predicting potential therapeutic, prognostic and diagnostic biomarkers