Salivary protiens and periodontitis

Completed

Conditions: non covid
Chronic periodontitis,

Registration Number: CTRI/2021/10/037617

Lead Sponsor: Self

Brief Summary: Inflammation is the central feature of diabetes mellitus and periodontitis.

The aim of the study is to evaluate the glycoconjugate levels ( free sialic acid and total protein) in the saliva of chronic periodontitis with and without diabetes mellitus type 2.

The study evaluates, free sialic acid, protein-bound sialic acid, and total protein.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 92

Inclusion Criteria

1 probing depth more than or equal to 5mm, 2 subjects with no periodontal treatment for the past 6 months, 3 oral glucose tolerance tests more than or equal to 200 mg per dl, or fasting plasma glucose more than or equal to 126 mg per dl or glycated Hb more than or equal to 6.5.

Exclusion Criteria

pregnant women, smokers, cardiovascular disease, immunodeficiency disorders, hemodialysis patients, bleeding disorders, rheumatoid arthritis, oral cancerous lesions.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
to evaluate glycoconjugate levels in chronic periodontitis associated with diabetes mellits type 2.	baseline 0

Secondary Outcome Measures

Name	Time	Method
comparing protein bound and free sialic acid levels and total protein with and without diabetes mellitus type 2	baseline 0

Trial Locations

Locations (1): Room No.5, Department of Periodontics, Narayana Dental College & Hospital
🇮🇳
Nellore, ANDHRA PRADESH, India
Room No.5, Department of Periodontics, Narayana Dental College & Hospital
🇮🇳Nellore, ANDHRA PRADESH, India
DrVijaykumar Chava
Principal investigator
9441978737
chava7@hotmail.com