jRCTs031220373已完成不适用
Randomized, double-blind, placebo-controlled parallel-group comparative study to evaluate the effect of high-dose nicotinamide mononucleotide (NMN) on aging
未提供0 个研究点目标入组 62 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 62
- 主要终点
- -
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized Controlled Trial
- 干预模型
- Parallel Assignment
- 主要目的
- Prevention Purpose
- 盲法
- Double Blind
入排标准
- 年龄范围
- 65age old over 至 No limit（—）
- 性别
- All
入选标准
- •Aged 65 years old or older at the time of informed consent is taken
- •Male or female
- •Able to attend all scheduled visits
- •Able and willing to give written informed consent
排除标准
- •Taking health food
- •With severe hearing loss or wearing a hearing aid in daily life
- •Taking more than 1 hour daily exercise for more than 6 months
- •With a pacemaker
- •Taking medicine, including Chinese medicine
- •Having history of treatment for cancer, heart failure and myocardial infarction
- •With atrial fibrillation, arrhythmia, liver failure, renal failure, cerebrovascular disease, rheumatoid arthritis and other chronic diseases except diabetes, dyslipidemia and hypertension
- •Suspected of having viral hepatitis, HIV or syphilis
- •With drug allergy or with food allergy to health food related to this study
- •Participated in other clinical trials within 3 months
- •Judged as ineligible by clinical investigators
结局指标
主要结局
-
Change from baseline in hearing ability after 24 weeks of treatment
次要结局
- Physical function(24 weeks)
- Blood tests(24 weeks)
- Biomarkers(24 weeks)
- DNA methylation age(24 weeks)
- Skin condition(24 weeks)
- Exercise tolerance assessed by the 6 minute walk test(24 weeks)
- Gut and oral microbiota(24 weeks)
- Number of mitochondria(24 weeks)
- Quality of Life(24 weeks)
- Correlation between blood NAD level and these items
研究者
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