The effect of low-dose radiotherapy on pain in mild osteoarthritis of the hip
Suspended
- Conditions
- osteoarthritis and hip joint degeneration10023213
- Registration Number
- NL-OMON41561
- Lead Sponsor
- Orbis Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Painful, low-grade osteoarthritis of the hip (Kellgren-Lawrence graad I-II)
Above 50 years old
Synovitis confirmed with ultrasound imaging
Ability and willingness to follow instructions and to return for follow-up evaluations
Exclusion Criteria
Patients diagnosed with reumathoid arthritis
Patients with osseous metastasis
Patients with rheumatoid factor > 20 kU/l or blood sedimentation rate > 20mm
Patients with a moderate or severe osteoarthritis grade (Kellgren-Lawrence graad III-IV)
Patients with a hip/spine dilemma
Prostethic implant in the affected joint
Not able or willing to undergo bone scintigraphy or blood sampling
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Objectives<br /><br>Primary objective.<br /><br>•To determine the effect of LDRT on pain sensation after 1,2, 3 and 6 months in<br /><br>early osteoarthritis of the hip, measured with a Visual Analogue Scale (VAS)</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary objectives<br /><br>•To determine the effect of LDRT on patient reported outcome measures (PROM)<br /><br>including WOMAC and Oxford Hip Score.<br /><br>•To determine the effect of LDRT on quality of life, assessed through the<br /><br>EuroQoL-5D questionnaire.<br /><br>•To investigate the relationship between effect of LDRT and level of synovitis,<br /><br>measured through ultrasound, bone scintigraphy and blood BSE level.</p><br>