Comparison of Apnea Tolerance in Two Positions of Patients With BMI 30-40

Not Applicable

Completed

• Conditions: General Surgery
• Interventions: Other: 25° head-up position; Other: 55° head-up position

• Registration Number: NCT03056820
• Lead Sponsor: University of Kansas Medical Center

Brief Summary

The purpose of this study is to compare the effect of the 25° head-up position versus the 55° head-up position on tolerable apnea time (TAT) after induction of general anesthesia in patients with a body mass index (BMI) of 30-40.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-05
• Primary Completion: 2011-03
• Study Completion: 2011-03
• Study First Submitted: 2017-01-27
• Status Verified: 2017-02
• Study First Submitted QC: 2017-02-14
• Last Update Submitted: 2017-02-14
• Study First Posted: 2017-02-17
• Last Update Posted: 2017-02-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

• American Society of Anesthesiologists (ASA) physical status I-III
• Body Mass Index (BMI) of 30-40
• Scheduled for an elective surgery that requires tracheal intubation

Exclusion Criteria

• Patients with abnormalities of the upper airway that require awake tracheal intubation
• Asthma
• Chronic obstructive pulmonary disease
• Congestive heart failure
• Pregnant patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
A - 25° head-up position	25° head-up position	Participants will be positioned at 25° angle for procedure.
B - 55° head-up position	55° head-up position	Participants will be positioned at 55° angle for procedure.

Primary Outcome Measures

Name	Time	Method
Tolerable Apnea Time (TAT)	Time between start of induction of general anesthesia (SpO2 100%) to decline of SpO2 94%, up to eight minutes	Measure of the TAT between groups to determine if the TAT is a function of the participant's position.

Secondary Outcome Measures

Name	Time	Method
Length of time to intubation (TTI)	Time between start of the tracheal intubation procedure to completion of tracheal intubation, up to 2 minutes
Peripheral arterial hemoglobin oxygen saturation (SpO2) trough	Time until SpO2 decreased to 92%, up to 8 minutes	Measure of the rebound SpO2. It is the lowest SpO2 reading reached subsequent to start of mechanical ventilation at the SpO2 value of 94% and it represents final completion of SpO2 decline.

Trial Locations

Locations (1)

University of Kansas Medical Center; 🇺🇸 Kansas City, Kansas, United States