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临床试验/NCT03391505
NCT03391505已完成不适用

Acute Effects of Physical Activity On Memory, Cognitive Performance and Brain Activity

University of Southern Denmark2 个研究点 分布在 1 个国家目标入组 81 人开始时间: 2018年2月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
81
试验地点
2
主要终点
Long-term Memory Accuracy Performance

研究概览

简要总结

The overall aim of the study is to investigate the effects of an acute bout of physical activity on cognitive performance and long-term memory in elementary school children. Elaborating, the study seeks to investigate the effect of the intensity of the physical activity on cognitive performance and long-term memory in preadolescent children.

详细描述

Based on a power analysis a total population of 100 children (four school classes) will be invited to participate in a 10-day protocol. The children will be randomly allocated, within their cluster (classes) and stratified for gender and soccer level, to one of 3 intervention groups. The groups consist of: A small-sides soccer game group (SSG), a walking soccer group (WSG) and a rest group watching soccer on TV (RES). At day 1 the children will complete a screening of their physical characteristics (height, weight, fat percentages, lean muscle mass and fitness status). On day 2 the children will complete a screening and a familiarization to the cognitive tasks used (cognitive performance and long-term memory) and the brain activity measuring devices (transportable EEG systems). On day 3 the children will complete the interventions, which first consist a long-term memory task, where the children will be asked to remember forty different pictures. Immediately after exposure to the forty pictures, the children will participate in 2 x 10 minutes of their respective interventions with 5 minutes break in between. During the break, the children will complete a short questionnaire to address their flow. Furthermore, during the intervention they will be equipped with heart rate monitors to quantify the physical demands of the intervention. Immediately after completing the 2 x 10 minutes interventions the children will be equipped with a transportable EEG system, and undergo a cognitive test (the Flanker task) to address their cognitive performance. The EEG recordings are used to measure the P3 amplitude and latency, biomarkers for cognitive performance. While equipping the children with the EEG system, the children will complete questionnaires about their participation. At day 10 the children will try to remember as many pictures of the forty pictures as possible to address the effect of the interventions on their long-term memory.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
10 Years 至 14 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Informed consent from the childrens´ legal guardians.
  • Physical, linguistic and mental competencies to complete the intervention and testing.

排除标准

  • Use of prescription-only drugs that kan affect learning ability.
  • Neurological diseases inclusive damages to the spinal cord.
  • Children who is not evaluated to being cable of completing the protocol among these psychological diseases or psychological unstable children.

结局指标

主要结局

Long-term Memory Accuracy Performance

时间窗: 7 days

Measures of response accuracy (%) during a tablet-based visual memory task

Cognitive Response Speed Performance

时间窗: 1 day

Measures of response speed (ms) during the computer-based Flanker task

Cognitive Response Accuracy Performance

时间窗: 1 day

Measures of response accuracy (%) during the computer-based Flanker task

Event-related brain potentials (P300)

时间窗: 1 day

Electroencephalographic measures (mV) of the neuroelectric system that occur in response to, or in or in preparation for, a discrete event.

次要结局

  • Fitness Status(1 day)
  • Flow(1 day)
  • Fat Percentage(1 day)
  • Maximal Heart Rate(1 day)
  • Height(1 day)
  • Weight(1 day)
  • Lean Body Mass(1 day)
  • Enjoyment(1 day)
  • Intervention intensity(1 day)
  • Motivation(1 day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Peter Krustrup

Professor

University of Southern Denmark

研究点 (2)

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