Prospective Study to Determine the Optimum Age for Routine DEXA Screening for Osteopenia/Osteoporosis in People With HIV Infection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 440
- 试验地点
- 1
- 主要终点
- Bone mineral density at Hip
研究概览
简要总结
The purpose of this study is to determine the bone mineral density in male and female patients with HIV infection according to age groups.
This will enable a practical approach to screening for osteoporosis and the management and prevention of fragility fractures in people with HIV.
In addition, all risk factors commonly associated with fragility fractures and osteoporosis are collected, as is HIV drug history.
Hence, as secondary outcomes, the associations with reduced bone mineral density can be ascertained.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years or above Not pregnant Able to comply with study observations and procedures Able to give fully informed consent
排除标准
- •Pregnant Less than 18 years of age Unable to comply with study procedures
结局指标
主要结局
Bone mineral density at Hip
时间窗: The outcome is measured within 6 months (0-6 months) after entry to the study.
Bone mineral density as determined by DXA scanning
次要结局
- Bone mineral density at spine (L4)(The outcome is measured within 6 months (0-6 months) after entry to the study.)
- Any lifetime fractures reported by subjects(At any stage during persons life up to and including the last visit for the volunteer to the study.)
- Vitamin D levels(The outcome is measured within 6 months (0-6 months) after entry to the study.)
研究者
Barry Stephen Peters
Reader and Consultant HIV Medicine, Head of Research Unit, Principle Investigator, Clinical Researcher
King's College London