Desmopressin acetate as an add-on therapy in patients with schizophreni?l
Phase 2
- Conditions
- schizophrenia.schizophrenia
- Registration Number
- IRCT201208071556N45
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion Criteria:1- Age between 18-50; 2-Diagnosis of Schizophrenia based on DSM- IV; 3- chronic Schizophrenia( duration of the disorder>2 years); 4- Minimum Score of 60 on Positive and Negative Scale; 5-receiving a constant dose of risperidone during the last month
Exclusion Criteria
1- Substance dependence during the last 6 months;2- IQ <70; 3-any other mental disorder on axis I; 4-Any serious medical or neurological problem ;5-receiving ECT during the last 14 days, 6- hepatic disease; 7-nursing or pregnant women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of schizophrenia. Timepoint: Baseline and weeks 2-4-6-8 after beginig of treatment. Method of measurement: Positive and Negative Syndrome Scale (PANSS).
- Secondary Outcome Measures
Name Time Method