The Association Between Molecular Typing of Treponema Pallidum and Treatment Efficacy and Clinical Findings

Phase 4

• Conditions: Syphilis
• Interventions: Drug: Benzathine Penicillin G

• Registration Number: NCT02871505
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

The investigators compare the treatment results and clicical presentations of different Molecular subtyping of Treponema pallidum

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08
• Study First Submitted: 2016-08-09
• Study First Submitted QC: 2016-08-15
• Study First Posted: 2016-08-18
• Status Verified: 2018-11
• Last Update Submitted: 2018-11-15
• Last Update Posted: 2018-11-16
• Primary Completion: 2020-08
• Study Completion: 2020-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

1. Pregnant woman
2. Known allergy to penicillin
3. RPR titers were found to be 1:8 or less

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Molecular subtyping (14d/f) of Treponema pallidum	Benzathine Penicillin G	Benzathine Penicillin G treatment
Molecular subtyping (others) of Treponema pallidum	Benzathine Penicillin G	Benzathine Penicillin G treatment

Primary Outcome Measures

Name	Time	Method
rapid plasma regain titer	6 months after treatment

Trial Locations

Locations (1)

Department of Dermatology and Venereology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; 🇨🇳 Beijing, China