Effect of Panretinal Photocoagulation on Confocal Laser Scanning Ophthalmoscopy and Stereo Photographic Parameters of the Optic Disc Topography in Diabetic Retinopathy Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- Cup area
研究概览
简要总结
This study analyzed diabetic patients without evidence of glaucoma who underwent panretinal photocoagulation to determine the effect on optic disc topographic parameters in non-glaucomatous patients with proliferative diabetic retinopathy (PDR).
详细描述
Glaucoma and proliferative diabetic retinopathy (PDR) are two very prevalent diseases that often coexist. Previous literature suggest that panretinal photocoagulation may somehow lead to optic disk cupping. Therefore, evaluation of the optic disc cupping and of possible glaucomatous damage in patients with diabetic retinopathy can be difficult, especially after PRP treatment. The purpose of this study is to determine the long-term effect of PRP on optic disc topographic parameters in non-glaucomatous patients with PDR using Heidelberg retina tomograph (HRT) parameters and stereo photography. The Investigators found that PRP does not cause morphological optic disk changes in diabetic PDR patients after one year of follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of PDR (due to type 1 or 2 diabetes mellitus)
- •intraocular pressure < 18 mmHg
- •nonglaucomatous optic disc characteristics at fundus examination
- •vertical cup-to-disc (C/D) ratio <0.7
- •absence of media opacities
排除标准
- •previous diagnosis of glaucoma
- •family history of glaucoma
- •neuroophthalmic disease
- •retinal artery or vein occlusion
- •optic disc neovascularization
- •diabetic macular edema (DME)
- •corneal opacity
- •previous laser photocoagulation treatment
结局指标
主要结局
Cup area
时间窗: 12 months
Change in cup area (mm2) measured by Heidelberg retinal tomograph (HRT) before and one year after PRP
次要结局
未报告次要终点