NCT05726877RecruitingNot Applicable
Determination of Optimal Positive End-expiratory Pressure in Prone Position During General Anesthesia Using Electrical Impedance Tomography in Pediatric Patient Under 17 Years of Age
Seoul National University Hospital1 site in 1 country51 target enrollmentStarted: October 17, 2022Last updated:
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 51
- Locations
- 1
- Primary Endpoint
- Optimal positive end-expiratory pressure (PEEP)
Study Overview
Brief Summary
This study aimed to investigate the differences in positive end-expiratory pressure titration in the supine and prone positions by age in pediatric patients under 17 years of age who received general anesthesia and then evaluate the hemodynamic stability.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 0 Years to 16 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients who are scheduled to undergo general anesthesia in the prone position
- •patients who are in age under 17 years
Exclusion Criteria
- •had cyanosis or chronic respiratory failure
- •had respiratory distress syndrome or bronchopulmonary dysplasia
- •had laryngotracheal diseases
- •had pulmonary hypertension
- •receiving oxygen therapy
Arms & Interventions
Experimental arm
Experimental
All patients will be enrolled in the same arm.
Intervention: ventilation strategy (Other)
Outcomes
Primary Outcomes
Optimal positive end-expiratory pressure (PEEP)
Time Frame: 60 minutes after prone positioning
result of decremental PEEP trial
Optimal positive end-expiratory pressure (PEEP)
Time Frame: 10 minutes after intubation
result of decremental PEEP trial
Secondary Outcomes
- end-expiratory lung impedance(60 minutes after prone positioning)
- vital signs(60 minutes after prone positioning)
- Impedance tidal variation(60 minutes after prone positioning)
- overdistension or atelectasis(60 minutes after prone positioning)
- regional ventilation delay(60 minutes after prone positioning)
- arterial blood gas analysis, if patients has arterial catheter(10 minutes after intubation & 60 minutes after prone positioning)
- center of ventilation(60 minutes after prone positioning)
- end-expiratory lung volume(60 minutes after prone positioning)
- regional respiratory system compliance(10 minutes after intubation)
- Impedance tidal variation(10 minutes after intubation)
- regional respiratory system compliance(60 minutes after prone positioning)
- overdistension or atelectasis(10 minutes after intubation)
- end-expiratory lung volume(10 minutes after intubation)
- end-expiratory lung impedance(10 minutes after intubation)
- regional ventilation delay(10 minutes after intubation)
- center of ventilation(10 minutes after intubation)
- vital signs(10 minutes after intubation)
Investigators
Study Sites (1)
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