Study of Opioid Immunosuppressive Effects

• Conditions: Opioid Abuse or Dependence

• Registration Number: NCT01881802
• Lead Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Brief Summary

This trial aims to investigate the effects of opioid-inducing immune suppression on opioid drug abused patients. The methods of the investigators research mainly includes the expression of morphine-related miRNAs in peripheral blood mononuclear cells and cytokine in plasma.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-03
• Status Verified: 2013-06
• Primary Completion: 2013-06
• Study First Submitted: 2013-06-03
• Study First Submitted QC: 2013-06-19
• Last Update Submitted: 2013-06-19
• Study First Posted: 2013-06-20
• Last Update Posted: 2013-06-20

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• subjects were excluded if they had a chronic systemic illness (cardiac, renal, pulmonary, hepatic, endocrine, metabolic, or autoimmune disorders) or
• a major psychiatric disorder or
• if they were abusing substances other than heroin (as determined by urine drug test result). For women, pregnancy was also a reason for exclusion.

Exclusion Criteria

• Control subjects with no history of drug or alcohol abuse were also excluded if they had
• major medical or psychiatric disorders

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
real-time quantitative polymerase chain reaction	up to 2 months

Secondary Outcome Measures

Name	Time	Method
enzyme-linked immuno sorbent assay	up to 2 months