Flushing of internalized percutaneous transhepatic biliary drainage catheters

Recruiting

• Conditions: biliary obstruction; 10019654

• Registration Number: NL-OMON54445
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 91

Inclusion Criteria

- Patient with obstruction of the bile duct(s) planned for internal external
PTBD;
- Proficient in Dutch language;
- Written informed consent.

Exclusion Criteria

- Age < 18 years;
- No informed consent;
- Pregnancy;
- Obstruction caused by gall stones;
- External PTBD catheter (without internalization);
- Patient has already a PTBD catheter;
- More than 1 PTBD catheter is placed at intervention.
- If the patient is non-communicative.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Median time-to-symptom-onset in patients with an internal external PTBD<br /><br>catheter without daily flushing compared to patients with an internal external<br /><br>PTBD catheter who daily flush the catheter</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Comparison of the number of re-interventions<br /><br>- Comparison of the events of cholangitis<br /><br>- Comparison of the decrease in bilirubin<br /><br>- Comparison of the quality of life<br /><br>- Comparison of the cost-effectiveness<br /><br>- Comparison of the mortality rate<br /><br>- Comparison of the number of catheter complications<br /><br>- Therapy adherence</p><br>