Post-surgical analgesic efficacy of mgso4 versus lignocaine with acetaminophen in asthmatic patients
Not Applicable
- Conditions
- pain.Pain, unspecified
- Registration Number
- IRCT20231124060161N2
- Lead Sponsor
- CMH Rawalpindi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
all ASA-I and II patients diagnosed with asthma by spirometry pre- and post-bronchodilator therapy with confirmation of reversibility presenting to the surgical department for elective laparoscopic cholecystectomy compliant and optimized on treatment.
Exclusion Criteria
major cardiac or respiratory disease
low ejection fraction
unoptimized for hypertension or diabetes
patients with cholecystitis, patients allergic to acetaminophen, MgSO4, lignocaine or nalbuphine
patient with a history of asthma exacerbation requiring admission in the last 8 weeks.
patients on oral or intravenous steroids for asthma
patients unwilling to be included in the study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Analgesia. Timepoint: 24hrs after first analgesics dose. Method of measurement: Visual Analogue Scale (VAS).
- Secondary Outcome Measures
Name Time Method Hypotension. Timepoint: 1,3,6 hours. Method of measurement: cardiac monitor, sphygmomanometer.;Respiratory depression. Timepoint: 1,3,6 hours. Method of measurement: pulse oximetry, cardiac monitor.;Nausea. Timepoint: 1,3,6 hours. Method of measurement: Visual assessment and patient complaints.;Vomiting. Timepoint: 1,3,6 hours. Method of measurement: Clinical assessment, patient complaints.