lidocaine effect on extubatio
- Conditions
- arangospasm..Postprocedural subglottic stenosisJ95.5
- Registration Number
- IRCT20211206053291N1
- Lead Sponsor
- Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
simple cardiac surgury(CABG or valvular)
No history of smoking and drug or alcohol addiction during the last 10 years before surgery
No history of any drug or food allergies
All patients took beta-blockers around the operation and in the morning
No history of lung problems (asthma, COPD, etc.) treated with oral or inhaled drugs
Dangerous arrhythmia during or after surgery
Hemodynamic instability including: cardiac instability (patients treated with epinephrine or levofed at doses above 1.1 µg / kg) and respiratory instability (po2=60mmhg or pco2=50) during postoperative time
Bleeding so much that the patient becomes a candidate for reoperation
Injection of lidocaine for any reason after surgery
EF drop after surgery
Use of ECMO or pump balloons after surgery
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cough occurs after extubation. Timepoint: The onset of cough is assessed before and during injection, 5 minutes after injection, and finally one minute after endotracheal tube removal and 10 minutes after. Method of measurement: The incidence of cough is measured by three criteria of cough, which include: 1- no cough or temporary cough following the exit of the endotracheal tube, 2- incidence of cough by breathing, and 3- persistent cough without respiratory stimulation when the endotracheal tube exits up to 10 minutes later. The questionnaire is mentioned.
- Secondary Outcome Measures
Name Time Method