Assessment of Physical Fitness and Activity in cardiac surgery patients in relation to cognitive function decline and perioperative morbidity

Completed

• Conditions: postoperative cognitive dysfunction/concentration and memoryloss after surgery; 10011082; 10009841

• Registration Number: NL-OMON41968
• Lead Sponsor: anesthesiologie- onderzoeksbureau

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

- Scheduled for elective cardiac coronary surgery, and booked for routine clinical assessment on the cardiosurgical preoperative screening unit.
- Able to stand and walk independently
- Able to participate in the online screenings module for cognitive function (ie able to operate a computer touch pad or mouse, and to read large text on a computer screen).
- They should be prepared to allow a researcher to visit them at home 3 months after their operation.
- Patients need to be able to perform the handgrip strength test on both sides.

Exclusion Criteria

- Exentended postoperative ICU stay is expected.
- Inability to understand or read Dutch instructions
- Recent history of depression or severe anxiety
- History of dementia or other neurological disorders
- History of stroke, or other severe cerebrovascular insults

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters will be:<br /><br>• Pre-operative levels of physical activity as assessed by the SQUASH<br /><br>questionnaire and the SenseWear activity meter<br /><br>• Pre-operative mobility/fitness as assessed by the get-up-and-go test<br /><br>• Pre- and operative muscle strength, as assessed by a simple mechanical device.<br /><br>• Development of POCD, defined as a decline of cognitive performance (relative<br /><br>to baseline) of >= 2 SD in 2 or more of the 4 cognitive tests. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcome parameters will include routinely recorded process and<br /><br>outcome variables.</p><br>