Study on the mechanism of Huayu Tongluo moxibustion improving Cd induced by T2DM from the relationship between DMN and hippocampus
- Conditions
- Cognitive decline in type 2 diabetes
- Registration Number
- ITMCTR2100005010
- Lead Sponsor
- The First Affiliated Hospital of Anhui University of traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. The diagnostic criteria were met;
2. Aged 45 to 75 years, right handedness;
3. Course of disease >= 1 year, MMSE < 27;
4. Close self-test and standard treatment with various hypoglycemic drugs, FPG <= 11 mmol / L;
5. There was no history of hypoglycemia;
6. Volunteer and sign informed consent.
1. MMSE>=27;
2. HAM-D>=7;
3. Other psychological or neurological disorders that are not related to diabetes;
4. Brain damage such as tumor or stroke;
5. History of alcohol or drug abuse;
6. Patients treated with insulin or insulin sensitizer;
7. Patients with MRI contraindications (pacemaker, claustrophobia, etc.);
8. Those who can't cooperate with the experiment (such as refusing to sign the informed consent and can't insist on the whole experiment).
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complex Graphics Test Scale;connection test scale;Montreal Cognitive Assessment Scale;Auditory Verbal Learning Test Scale;
- Secondary Outcome Measures
Name Time Method serum insulin;C-peptide;fasting blood sugar;glycosylated hemoglobin;