To compare lignocaine alone and in combination with dexmedetomidine for intravenous regional anaesthesia for upper limb surgery.

Completed

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2019/05/018918
• Lead Sponsor: Jln Medical College ajmer

Brief Summary

The aim of the study is “**to compare anaesthetic properties of 0.5% lignocaine alone and in combination with Dexmedetomidine in intravenous  regionalanaesthesia in upper limb orthopaedic surgeryâ€**in the terms of:-

 **Objectives:**

 **Primary:**

1.Onset of sensory and motor block.

2. duration of  analgesia.

**Secondary:**

1.Duration of sensory and motor block.

2.Torniquet pain.

3.Need for analgesic supplements

4.Post operative sedation

5. Adverse effects including nausea, vomiting, bradycardia, hypotension, desaturation and others, if  any

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-01-11
• Study Start: 2019-08-05
• Study Completion: 2019-08-21

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age between 20 to 55 years, of either sex.
• 2.Body weight 35 to 80 kg.
• 3.Patients belonging to ASA Class I and II.
• Patients undergoing upper limb surgeries of duration less than 45 minutes.
• 5.Patient free from any associated acute or chronic systemic illness.

Exclusion Criteria

• Patients with contraindications to tourniquet application like sickle cell anemia, cellulitis, sepsis, open wound in that extremity, etc.
• Patients hypersensitive to lignocaine 3.
• Patient not willing for IVRA 4.
• Patient already on analgesics (opioids, NSAIDS) 5.
• Patients receiving beta blockers or cardiac drugs.
• History of convulsion, allergy to the drug used, bleeding disorder, severe neurological deficit, thyroid disorder.
• Patient with history of respiratory, cardiac, hepatic or renal disease (necessitating classification in ASA Class III or above).
• Inadequate block necessitating institution of general anaesthesia for continuation of surgical procedure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality and duration of post-operative analgesia	duration of study is around 1 year

Secondary Outcome Measures

Name	Time	Method
1.Torniquet pain.	2. Need for analgesic supplements

Trial Locations

Locations (1)

Jln Medical College ajmer; 🇮🇳 Ajmer, RAJASTHAN, India

Jln Medical College ajmer

🇮🇳Ajmer, RAJASTHAN, India

Dr Shilpi tada

Principal investigator

8890026413

drshilpitada@gmail.com