Maximal fat oxidation during exercise: impact of nutritional status and exhaustio

Completed

Conditions: niet van toepassing (inspanningsfysiologie)
na

Registration Number: NL-OMON49381

Lead Sponsor: Wageningen Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 40

Inclusion Criteria

* Apparently healthy (self-reported)
* aged between 20 and 35
* BMI between 18.5 to 27 kg/m2
* Recreationally active, defined as minimal of 3 hours training per week, and a
maximum of 10 hours a week
* The sport a participant is engaged in should be a game sport, endurance
sport, or should at least contain a major endurance component. Examples of
sports that can be included are: distance running, cycling, triathlon,
crossfit, and game sports like soccer, rugby, handball, hockey,
* For part 2 subjects should be used to prolonged cycling exercise
* Able to be present and participate at all test days and willing and able to
follow prescribed interventions

Exclusion Criteria

* Inactive (defined as <3 hours of training per week)
* Non-recreational athlete (>10 hours of training per week)
* active in a sport without a major endurance component
* Smokers, defined as someone who has smoked regularly in the previous year.
* Excessive alcohol consumption (i.e. more than 14 units for males per week; 7
units for females)
* Drug use
* The more *extreme* diets (like veganism, ketogenic diet, raw-food, carnivore
diet etc.)
* Participation in another biomedical study possibly interfering with the study
results within 1 month before the first study visit
* Inability to participate and/or complete the required measurements
* People working for the department of Human Nutrition and Health
not having a GP

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are the MFO and FATmax as assessed with indirect<br /><br>calorimetry (VO2, VCO2) during a graded exercise test (35W/ 3min protocol). In<br /><br>order to calculate these values oxygen consumption (VO2), and CO2 production<br /><br>(VCO2) are measured. From these values the RER can be calculated, and fat<br /><br>oxidation will be quantified according to by the stoichiometric equations<br /><br>Frayn (1983). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Other parameters that can be obtained during the graded exercise test are: peak<br /><br>sustained power output (expressed in Watt), maximal oxygen consumption<br /><br>(VO2max), (maximal) heart rate and the respiratory exchange ratio (RER) during<br /><br>different stages of the graded exercise protocol.<br /><br>In addition, body composition, training history and dietary intake will be<br /><br>measured</p><br>