NCT04349566已完成不适用
Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases
Mads Peter Godtfeldt Stemmerik1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2020年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Change in biomarkers
研究概览
简要总结
The purpose of the study is to explore the biomarker Fast Troponins response to exercise in patients with Becker muscular dystrophy, Limb-girdle muscular dystrophy and McArdle disease
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The ability to cycle
- •No concurrent medical condition that could interfere with interpretation of the results
- •Molecular diagnosis of the specific condition in specified patient groups or healthy control
- •No active muscle injury on the test day (caused by recent exercise, seizures, trauma, etc.)
排除标准
- •Competing conditions at risk of compromising the results of the study
- •Cardiac or pulmonary disease contraindicating peak exercise testing or strenuous exercise
- •Veins that are too difficult to puncture for blood sampling, evaluated by the investigator
- •Severe muscle weakness, that prevents the subject completing the exercise test, evaluated by the investigator
结局指标
主要结局
Change in biomarkers
时间窗: 24 hours
Change in Fast and slow Troponin I after muscle damage
次要结局
未报告次要终点
研究者
Mads Peter Godtfeldt Stemmerik
MD
Rigshospitalet, Denmark
研究点 (1)
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