CTRI/2025/04/085626尚未招募不适用
A Randomised double-blind controlled trial to compare the block efficacy and duration of post-operative analgesia between dexamethasone and dexmedetomidine as adjuvant to local anaesthesia in ultrasound-guided Supraclavicular brachial plexus block in patients undergoing upper limb orthopaedic surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- Duration of postoperative analgesia
研究概览
简要总结
This study is to compare the duration of postoperative analgesia and efficacy with two different adjuvants i.e. 8mg dexamethasone and 50mcg dexmedetomidine added to 2% lignocaine with adrenaline plus 0.5% bupivacaine in two different groups when used in adult patients undergoing ultrasonography guided supraclavicular brachial plexus block for upper limb orthopaedic surgeries. There is however paucity of data regarding dexamethasone and dexmedetomidine as adjuvants for local anaesthetics and therefore this study is planned to research the same.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •American society of Anesthesiologists (ASA) physical status I/II patients
- •Patients aged 18 years and above
- •Patients weight more than 50Kg
- •Patients of both male and female gender
- •Patients scheduled for emergency, semi emergency or elective upper limb orthopaedic (elbow, forearm and hand) surgery.
- •Patients willing to take part in the study.
- •Hemodynamically stable patient with Heart rate 60 to 85/min, MAP 60 to 75mmHg.
排除标准
- •Patients refusing to voluntarily participate in the study
- •Patients less than 18 years of age
- •Pre-existing peripheral neuropathy of upper limb
- •Patients with Bleeding disorders
- •Patients with infection at injection site
- •Patients with pneumothorax
- •Patients on adrenoreceptor agonist or antagonist therapy
- •ASA III and above
- •Pregnancy
- •Known hypersensitivity to the study drugs.
结局指标
主要结局
Duration of postoperative analgesia
时间窗: 24 hours
次要结局
- Onset and quality of sensory and motor block, Haemodynamic stability(3 hours)
研究者
Dr LAKSHMISRAVYA KETHARI
MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES, SEVAGRAM, WARDHA
研究点 (1)
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