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Metabiomics Colon Cancer Clinical Research Study

Conditions
Colonic Neoplasms
Registration Number
NCT02151123
Lead Sponsor
Metabiomics Corp
Brief Summary

The specific aim of the study is to determine the false negative rate of the Metabiomics Colon Polyp and Colorectal Cancer Assay for Cancer.

Detailed Description

The purpose of this study is to conduct clinical research to investigate the association of the gut microbiome with colonic neoplasia. In this case several types of gut microbiome samples will be collected from patients undergoing colectomy for colonic adenocarcinoma; those samples will be tested by Metabiomics Colon Polyp and Colorectal Cancer Assay and the percentage of false negative (test returns a negative for cancer) results determined.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Recently diagnosed with colorectal cancer (CRC) and scheduled for colectomy
  • Male or female,
  • Age: 18-95 years,
  • Able to comprehend, sign, and date the written informed consent form (ICF),
  • Able to give informed consent in English
  • Women and minorities will be included.
Exclusion Criteria
  • History of Inflammatory Bowel Disease
  • Antibiotics within 2 weeks of sample collection.
  • Colonoscopy, colon prep or bowel contrast agent within 7 days prior to sample collection
  • Any radiation therapy

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
False negative rate of test for colon cancerimmediately post surgery

The False Negative Rate is calculated as (100\*False Negative) /(True Positive + False Negative).

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Colorado School of Medicine Anschutz Medical Campus

🇺🇸

Aurora, Colorado, United States

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