Effects of Pomegranate Juice on Oxidative Stress in Patients With type2 Diabetes
Phase 4
Completed
- Conditions
- Diabetes Type 2
- Interventions
- Behavioral: lifestyle modificationDietary Supplement: pomegranate juice
- Registration Number
- NCT02559843
- Lead Sponsor
- National Nutrition and Food Technology Institute
- Brief Summary
Introduction: Diabetes mellitus a chronic diseases, is the most common and important metabolic disease in human. Increased free radicals production due to hyperglycemia produces oxidative stress which worsens the disease and its complications. Pomegranate juice has antioxidant and antiatherosclerotic properties. The present study was planned to evaluate the effects of pomegranate juice consumption on glycemic control, lipid profile,blood pressure and oxidative stress in patients with type 2 diabetes
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Age of 40-65 years
- Body Mass Index 18.5-30
- Fasting blood glucose ≥ 126 mg/dl
Exclusion Criteria
- Smoking
- insulin for blood glucose control
- taking estrogen or progesterone (if female)
- Taking antioxidant supplements
- suffering from any other chronic diseases
- Participants are also excluded if they missed more than 10% of their pomegranate juice packs
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description control lifestyle modification lifestyle modification including dietary recommendations pomegranate juice pomegranate juice 200 ml pomegranate juice + lifestyle modification
- Primary Outcome Measures
Name Time Method total antioxidant capacity 6 weeks
- Secondary Outcome Measures
Name Time Method fasting blood glucose 6 weeks
Trial Locations
- Locations (1)
NNFTRI clinic
🇮🇷Tehran, Iran, Islamic Republic of