Safety and efficacy of steroid pulse therapy to prevent stricture after endoscopic submucosal dissection (ESD) for esophageal cancer
- Conditions
- early esophageal cancer
- Registration Number
- JPRN-UMIN000010878
- Lead Sponsor
- Fukushima Medical University School of Medicine, Department of Gastroenterology
- Brief Summary
The stricture rate was 54.5% (6/11). The median time until stricture development was 15 days. The median number of EBD sessions required was 2.5. The median duration of EBD was 14.5 days. AEs related to steroid pulse therapy and postprocedure complications were not observed.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 11
Not provided
1. Patient with active peptic ulcer in stomach and duodenum. 2. Patient has a history of tuberculosis. 3. Patients who had an acute myocardial infarction. 4. Patients with uncontrolled diabetes mellitus. 5. Patients with continuous systemic steroids medication. 6. Patients with continuous systemic NSAIDs. 7. Patients temporary interruption of antiplatelet agents and anticoagulants is not possible. 8. Patients with severe mental disease or psychotic manifestation. 9. Patients who have been judged as inappropriate for this study for any reasons by the concerning investigation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Strictures after ESD
- Secondary Outcome Measures
Name Time Method Safety of steroid pulse therapy