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EValuation of the Antioxidant and Anti-inflammatory Capacity of Nutraceutical IMMU·SYSTEM Food Supplement (EVAANIS)

Not Applicable
Completed
Conditions
Oxidative Stress
Interventions
Other: Placebo
Dietary Supplement: Immusystem
Registration Number
NCT04912947
Lead Sponsor
Complife Italia Srl
Brief Summary

The aim of the study is to verify the effectiveness of Nutraceutical IMMU·SYSTEM Dietary supplement in reducing the levels of oxidative stress and inflammation in a sample of healthy adult subjects with high baseline levels of oxidative stress.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Caucasian ethnicity;
  • Age between 30 and 65 years;
  • Smokers who have smoked at least 100 cigarettes in their lifetime and smoke at least 10 cigarettes a day;
  • Sportsmen who have been playing sports for at least 6 months between 4 and 8 hours per week;
  • Signature of informed consent.
Exclusion Criteria
  • Systemic pathologies;
  • Active drug therapy;
  • Estrogen-progestogen therapy;
  • Pregnancy;
  • Allergies to the components of the raw material under study.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
PlaceboPlaceboOne cp/day of Placebo for 3 months
Dietary supplementImmusystemOne cp/day of the IMMUSYSTEM food supplement for 3 months
Primary Outcome Measures
NameTimeMethod
Change in Erythrocytes GSH/GSSG ratioMonth 1

Change from Baseline reduced/oxidized glutathione ratio in erythrocytes at 1st Month

Secondary Outcome Measures
NameTimeMethod
Change in Immune system activityMonth 1

Change from Baseline of Serum levels of IFN-γ at 1st Month

Trial Locations

Locations (1)

University of Calabria

🇮🇹

Rende, CS, Italy

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