Study on the initial treatment of Whipple's disease
Completed
- Conditions
- Whipple's DiseaseWhipple's diseaseDigestive System
- Registration Number
- ISRCTN45658456
- Lead Sponsor
- German Red Cross Hospital Neuwied (DRK Krankenhaus Neuwied)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
Patients with Whipple-typical macrophages in the duodenal mucosa or elsewhere confirmed by the reference pathologist
Exclusion Criteria
1. Current antimicrobial therapy for more than 1 month
2. Previous and unsuccessful antimicrobial therapy for Whipple's Disease
3. Recurrence of Whipple's Disease
4. Human Immunodeficiency Virus (HIV) infection, pregnancy, manifest tumor disease (except lymphoma)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Remission maintained for three years
- Secondary Outcome Measures
Name Time Method Prospective collection of clinical, immunological, and pathological data concerning diagnosis and course of Whipple's disease.