Planning Margin Requirements for Pediatric Radiation Oncology
Completed
- Conditions
- Pediatric Radiation
- Registration Number
- NCT00704613
- Lead Sponsor
- St. Jude Children's Research Hospital
- Brief Summary
The planning target volume (PTV) and planning organ at risk volume (PRV) margins used for pediatric radiation therapy are empiric, and quantitative assessment of these margins is needed to improve therapy planning and delivery.
- Detailed Description
Data will be gathered to develop a model to quantify the setup margin (SM) portion of the planning target volume (PTV) margin for pediatric tumor sites according to age, localization technique, treatment position, and the use of general anesthesia. Patient specific PTV and PRV margin recommendations will be developed based on the number of participants.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 375
Inclusion Criteria
- Patients will receive conformal or intensity-modulated radiation therapy (3D or IMRT).
- Research participant or legal guardian/representative gives written informed consent.
Exclusion Criteria
- Unwillingness of research participant or legal guardian/representative to give written informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acquire data to develop setup margin (SM) portion of the planning target volume (PTV) margin for pediatric tumor sites according to age, localization technique, treatment position, and the use of general anesthesia. 4 year
- Secondary Outcome Measures
Name Time Method Estimate the number of patients required to develop a patient specific PTV and RTV margin recommendations. 4 year
Trial Locations
- Locations (1)
St. Jude Children's Research Hospital
🇺🇸Memphis, Tennessee, United States