The Comparison of two methods of endotracheal tube cuff pressure regulation on atelectasis in patients under mechanical ventilatio

Not Applicable

• Conditions: atelectasis.; Pulmonary collapse

• Registration Number: IRCT2017091319677N4
• Lead Sponsor: Vice Chancellor for Research Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 220

Inclusion Criteria

age above 18 ; normal BMI (18.5-24.9) ; intubated through endotracheal tube (orotracheal) ;patients under mechanical ventilation and open heart surgery and CABG; FEV1/FVC > 0.7 (based on spirometery);chest x ray (based on radiologist's diagnosis) and history and examination(by Heart anesthetist)not to mention to acute or chronic pulmonary disease; heart failure ; immunodeficiency ;absence of chronic pulmonary disease(COPD) ; asthma ;patients with severe valve failure ; laryngeal disease or laryngeal anomalies.
Exclusion criteria: Patients with difficult intubation in 2 or more than 2 try ; reoperation due to post surgery critical condition ( more than 1000 cc drainage ; heart tamponade ) ; history of Pulmonary diseases in last 2 months.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Air leackage and atelectasis. Timepoint: 24 hours after the intervention. Method of measurement: auscultation.

Secondary Outcome Measures

Name	Time	Method
Endotracheal cuff pressure with volume-time curve technique. Timepoint: after admition to ICU and hemodynamic stabilization and temperture 35.5 , 37 with 20 minute interval. Method of measurement: Pressure gauge manometer.;Endotracheal cuff pressure without any audible sound of air leakkage technique. Timepoint: after admition to ICU and hemodynamic stabilization and temperture 35.5 , 37 with 20 minute interval. Method of measurement: Pressure gauge manometer.;Arterial oxygen pressure. Timepoint: 20 minute after extubation. Method of measurement: Arterial blood gas test(ABG).;Cross clamp time. Timepoint: during surgery. Method of measurement: Clock Gauge.;Body tempreture. Timepoint: after admition to ICU and 3 times after surgery in 20 minute intervals. Method of measurement: termometer.