The effect of low-dose volatile anesthetics on intraoperative evoked potential monitoring during anesthesia using remimazolam: a randomized controlled trial
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0007534
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion criteria
- American Society of Anesthesiologists physical status I~III
- 20 years old = Age < 80 years old
- Patients who are scheduled for elective cervical spine operation with intraoperative evoked potentials monitoring
- Patients who received written informed consent
Exclusion criteria
-Patients with tolerance or hypersensitivity to benzodiazepine
-Patients with dependence or addiction to psychotropic drugs or alcohol
-Patients with previous brain-related neurosurgery
-Patients with inserted status of intracranial device
-Pregnant and lactating women
-Patients with pacemaker insertion which may interfere evoked potentials test
-Patients with acute narrow angle glaucoma
-Patients with moderate hypersensitivity to Dextran40
-Patients with history of malignant hyperthermia or having genetic susceptible malignant hyperthermia
-Previous hypersensitivity history to halogenated inhalation agents
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change of amplitude and latency of evoked potentials exam
- Secondary Outcome Measures
Name Time Method The change of amplitude and latency of evoked potentials exam