Evaluation of melatonin on insomnia and daytime sleepiness associated with comisa
- Conditions
- Comorbid insomnia and obstructive sleep apnea.Obstructive sleep apnea (adult) (pediatric)G47.33
- Registration Number
- IRCT20220105053635N1
- Lead Sponsor
- Prescribing and rational use of medicine research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Age: 18-65 years old
Moderate- severe OSA ( apnea -hypopnea index = 15 times per hours)
Using CPAP for a minimum duration of one month
PSQI questionnaire point should be =5
The patient declares his / her commitment to strictly follow the study instructions, participate in visits and take interventions.
Severe pulmonary disease ( life expectancy less than 6 months)
Severe heart disease ( life expectance less than 6 months)
Severe neurologic disease ( example: dementia, Parkinson disease)
Major psychiatric disorder ( drug users, bipolar disorder, psychiatric disease in 3 months ago
Using drugs which interfere with sleeping and breathing
Known allergic reactions to melatonin according to past allergic history
Pregnancy or lactation
Hypothyroidism
Narcolepsy
Restless leg syndrome
Shift workers
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method