The effect of melatonin in patients with diabetic nephropathy
Phase 3
Recruiting
- Conditions
- diabetic nephropathy.Glomerular disorders in diabetes mellitus (E10-E14 with common fourth character .2†)N08.3*
- Registration Number
- IRCT20150606022562N5
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
GFR 15 to 89 ml per minute
Moderate blood pressure (systolic pressure 140-160 and diastolic pressure 80-100 mmHg)
No specific cardiovascular disease, cancer, inflammatory diseases, autoimmune and hyper or hypothyroidism
Non-presence of urinary tract infection and other factors of proteinuria
Exclusion Criteria
Special illness that leads to hospitalization.
High blood pressure (systolic pressure upper than 160 and diastolic pressure upper than 100 mmHg)
Unwillingness to cooperate
Taking fluvoxamine and any antioxidant supplement
Working at night shifts
Smoking and alcohol consumption
Breastfeeding and pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Insulin. Timepoint: At the beginning of the study and 12 weeks after intervention. Method of measurement: Elisa kit.;Insulin resistance. Timepoint: At the beginning of the study and 12 weeks after intervention. Method of measurement: HOMA formula.
- Secondary Outcome Measures
Name Time Method