Investigating the effect of Melatonin supplement on the incidence of Delirium After Coronary Artery Bypass Graft surgery

Phase 3

Recruiting

Conditions: Incidence of Delirium After Coronary Artery Bypass Surgery.
Postoperative delirium
F05.8

Registration Number: IRCT20230820059193N1

Lead Sponsor: Karaj University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 146

Inclusion Criteria

Patients over 18 years of age, whose blood supply disorder to the heart makes them candidates for Coronary Artery Bypass Graft surgery
Patients who have no problem understanding Persian language
Signing the consent form by the patient (Consent is obtained from patients in written and verbal form)

Exclusion Criteria

People who have a history of allergic reaction to Melatonin or other ingredients in the pill
Patients who suffered cardiac and respiratory arrest
Patients who Have a history of mental disorders such as Psychosis and Mental Retardation
Patients who take Antipsychotic drugs
Patients with a history of Seizures
Patients with a history of Delirium
Patients with Alzheimer's
Patients with severe Kidney and Liver failure
Patients with Alcohol or drug addiction
Patients who need reoperation due to abnormal bleeding
Patients who are deaf
Patients who do not have the ability to speak to answer the questions in the questionnaire
Patients who are unable to swallow oral Melatonin
Patients who are candidates for emergency surgery
Pregnant and Lactating women
If older people had medicines that interfered with my research
Older people who are not able to participate in this plan for any reason

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The rate of Delirium after surgery during the first 5 days after surgery. Timepoint: Investigation and recognition of confusion and monitoring of Delirium in patients of special care department is done on the day of operation and up to two days after the operation. Method of measurement: The confusion assessment-special care (CAM-ICU) questionnaire is used to investigate and recognize confusion and monitor delusions.

Secondary Outcome Measures