MRI as Alternative to CBCT for the Assessment of Furcation Involvement in Molars

Not yet recruiting

• Conditions: Periodontitis; Periodontal Diseases; Furcation Defects

• Registration Number: NCT06116487
• Lead Sponsor: Medical University of Vienna

Brief Summary

Aim of this prospective study is to compare magnetic resonance imaging (MRI) and cone beam computed tomography (CBCT) to diagnose furcation involvement (FI) in molars in patients with periodontitis. The focus is on the differentiation of grad II and III according to Hamp et al. 1975. 140 molars (70 upper and 70 lower) will be investigated with CBCT and MRI. Due to the absence of ionic radiation MRI might be a radiation free diagnostic tool to assess FI in the future without harmful radiation for the patient. Patients of the Dental Clinic, Medical University of Vienna, who need a CBCT and have a clinically diagnosed FI can be a participant of this clinical trial and do in addition to their CBCT a MRI. The accuracy of MRI will be compared to the diagnostic gold standard CBCT. If patients need additional periodontal treatment, e.g., periodontal surgery, a subgroup will also be analysed with intraoperative measurements.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-10
• Study First Submitted: 2023-10-25
• Study First Submitted QC: 2023-10-31
• Last Update Submitted: 2023-10-31
• Study First Posted: 2023-11-03
• Last Update Posted: 2023-11-03
• Study Start: 2023-11-20
• Primary Completion: 2024-09-20
• Study Completion: 2024-12-20

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• Patients with FI grade II or III, patients who need a CBCT, not pregnant

Exclusion Criteria

• Patients with contraindications to perform a MRI

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
horizontal furcation defects according to Hamp 1975	day 1	Grad 0, I, II, III

Secondary Outcome Measures

Name	Time	Method
vertical bone loss	day 1	measured in mm
horizontal bone loss	day 1	measured in mm

Trial Locations

Locations (1)

Medical University of Vienna, Clinic of Dentistry; 🇦🇹 Vienna, Austria