The Efficacy of Photobiomodulation in the Treatment of Anti-MAG-Induced Peripheral Neuropathy: LASER-MAG Study.
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 10
- 试验地点
- 1
研究概览
简要总结
Patients treated in the hematology department of the Quimper/Cornouaille Hospital Center for IgM monoclonal gammopathy with anti-MAG and symptomatic peripheral neuropathy often reach a therapeutic impasse.
The treatment of neuropathic pain is complex, but recently a new non-pharmacological therapy, photobiomodulation, has shown evidence of efficacy and improved quality of life in the treatment of these peripheral neuropathies.
This new therapy uses low-intensity lasers; it is non-invasive, athermic, and has no reported side effects. The general principle is to expose tissues to visible light in the red and near-infrared spectrum to elicit a biological response.
The study aims to evaluate the efficacy and tolerability of photobiomodulation in this population of patients with anti-MAG neuropathy.
详细描述
The protocol includes 16 photobiomodulation sessions, with monitoring of disability scores (ONLS, R-ODS), pain scores (NPSI), and quality of life scores (QLQ C30, QLQ CIPN20).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •IgM gammopathy with the presence of anti-MAG antibodies
- •symptomatic peripheral neuropathy
- •patient agreement
排除标准
- •Patients with a solid tumor located in areas exposed to PBM
- •Patients under legal guardianship (guardianship, conservatorship...)
- •cognitive disorders
- •Peripheral neuropathy of other aetiologies
- •Declining to participate
研究组 & 干预措施
patients
patients with anti-MAG neuropathy due to IgM monoclonal gammopathy
干预措施: photobiomodulation (Radiation)
研究者
Madame Rameau
doctor
Centre Hospitalier de Cornouaille