The effect of vitamin D on recurrence of chronic rhinosinusitis associated with nasal polyposis

Phase 3

Recruiting

• Conditions: J32.9; Chronic rhinosinusitis with nasal polyposis.; Chronic sinusitis, unspecified

• Registration Number: IRCT20211026052878N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients referred to Amiralam Hospital with chronic nasal sinusitis with polyposis

Exclusion Criteria

Dissatisfaction
Getting Covid 19 and getting vitamin D followed while studying
Patients with acute complications of chronic sinusitis
Taking immunosuppressive drugs
Contraceptive drug use (OCP)
Taking Anti TB drugs
Patients with active infection
Recent hypercalcemia or history of hypercalcemia
Get anticonvulsant medicine
Nephrolithiasis
Recent tanning history
Pregnancy
Breastfeeding
History of malabsorption
Vitamin D levels above 80
Continuous vitamin D3 supplementation over 400 units per day
Acute exacerbation of acute bacterial sinusitis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient score in SNOT-22 questionnaire. Timepoint: One month, three months and six months after surgery. Method of measurement: The Sino-Nasal Outcome Test (SNOT-22).;Patient score in Lund-Mackay score of CT scan. Timepoint: One month, three months and six months after surgery. Method of measurement: Lund-Mackay score of CT scan.;Patient score in Lund-Kennedy score. Timepoint: One month, three months and six months after surgery. Method of measurement: Lund-Kennedy score.